- Docente: Valerio Cozzani
- Crediti formativi: 6
- SSD: ING-IND/27
- Lingua di insegnamento: Inglese
- Moduli: Valerio Cozzani (Modulo 1) Ernesto Salzano (Modulo 2) Giordano Emrys Scarponi (Modulo 3)
- Modalità didattica: Lezioni in presenza (totalmente o parzialmente) (Modulo 1); Lezioni in presenza (totalmente o parzialmente) (Modulo 2); Lezioni in presenza (totalmente o parzialmente) (Modulo 3)
- Campus: Bologna
- Corso: Laurea Magistrale in Ingegneria chimica e di processo (cod. 8896)
Conoscenze e abilità da conseguire
Il corso fornirà nozioni su operazioni unitarie e apparecchiature specifiche dell’industria farmaceutica. Verranno inoltre introdotti criteri e procedure per la progettazione di processo, il controllo di qualità e la certificazione.
Contenuti
Requirements/Prior knowledge
A prior knowledge and understanding of local and integral balances of mass and energy, fluid dynamics models (perfect mixing and plug flow) is required to attend with profit this course.
In addition, students should master the utilization of spreadsheets.
Fluent spoken and written English is a necessary pre-requisite, because all lectures and tutorials, and all study material will be in English.
Program
Illustration of objectives and aims of the course.
Characteristics and peculiarities of the pharmaceutical industry. Outline of pharmaceutical legislation. The quality of the product.
Fundamentals of chemical kinetics for the synthesis of Active Pharmaceutical Ingredient (API)
The determination of the shelf-life of pharmaceutical products.
Viable methods for the kinetic analysis in the synthesis of API in batch and continuous reactors.
Sterilization of pharma products: decimal decay time, lethality time, batch and continuous reactor for the sterilization
Sterilization processes at variable temperatures
Vaporization and concentration processes
Drying processes
Batch distillation
Case studies presented by professionals
Testi/Bibliografia
Chemical Engineering in the Pharmaceutical Industry: Active Pharmaceutical Ingredients, Second Edition, D.J. am Ende and M.T. am Ende (Eds.), 2019 John Wiley & Sons, Inc.
Metodi didattici
Power point lecture presentations, demonstrations and practical classes.
Lectures by professionals.
Modalità di verifica e valutazione dell'apprendimento
Achievements will be assessed by means of a written test which consists of the solution of two exercises (module 2) and open questions (2 to 5 questions) (module 3)
Higher grades (from 25/30 to 30/30) will be awarded to students who demonstrate an organic understanding of the subject, a high ability for critical application, a clear and concise presentation of their ideas, and an appropriate use of technical language.
A failing grade will be awarded if the student shows knowledge gaps in key concepts of the subject, inappropriate use of language, and/or logic failures in the analysis of the subject.
Strumenti a supporto della didattica
Teaching material including PowerPoint slides, lecture notes are available to the students via the Virtuale Platform.
Material includes the analysis of case studies, examples and illustration of the solutions.
Orario di ricevimento
Consulta il sito web di Valerio Cozzani
Consulta il sito web di Ernesto Salzano
Consulta il sito web di Giordano Emrys Scarponi
SDGs
L'insegnamento contribuisce al perseguimento degli Obiettivi di Sviluppo Sostenibile dell'Agenda 2030 dell'ONU.