00148 - Organic Chemistry

Learning outcomes

The course aims to provide basic notions on the structure and reactivity of the main functional groups of organic molecules with brief insights into the mechanisms. Students will also acquire basic knowledge of some classes of organic compounds of industrial interest used in agrochemical, pharmaceutical, nutraceutical, cosmetic, in the development of pesticides, fertilizers and paints, in the dyes and surfactants industry and widely used in everyday life. The principles of green chemistry and sustainable chemistry of the REACH regulation (Registration, Evaluation, Authorization and restriction of CHemicals) and of the CLP regulation (Classification, Labeling and Packaging) will be introduced.

Course contents

1. Introduction to organic chemistry and the concept of functional group.
2. IUPAC nomenclature of organic compounds.
3. Basic notions on the structural and reactivity of the most common functional groups: alkanes, alkenes, alkynes, halides, alcohols, thiols, ethers, amines, aromatic hydrocarbons, aldehydes, ketones, carboxylic acids and their derivatives (acyl halides, anhydrides, esters, amides).
4. Basic notions of stereochemistry and properties of stereoisomers: enantiometers, distereoisomers and meso compounds; configuration and R / S descriptors. Racemic mixtures.
5. Organic compounds of industrial interest: agrochemicals, food, pharmaceuticals and nutraceuticals, cosmetics, paints, dyes and surfactants.
6. Principles of green chemistry and sustainable chemistry.
7. REACH regulation (Registration, Evaluation, Authorization and restriction of CHemicals) and the CLP regulation (Classification, Labeling and Packaging).

Readings/Bibliography

Suggested books:

• Introduzione alla chimica organica; William H. Brown, Thomas Poon; Edises.
• Fondamenti di chimica organica; Janice Gorzynski Smith; McGraw-Hill.

Teaching methods

• Lectures (4 CFU, 32 h) in which the topics of the program are illustrated and discussed with the support of power point slides.
• Exercises (2 CFU, 20 h) in which students, individually and in groups, will be involved in solving simple exercises on the nomenclature, identification and retrosynthesis of simple organic molecules.

Assessment methods

Final exam

Learning is verified through the final exam which takes place as a written exam to evaluate knowledge and the ability to solve simple Organic Chemistry problems.

The exam is considered pass with an overall grade greater than or equal to 18/30.

Ongoing test

An ongoing test relating to the part of the program already carried out up to that date will be approximately fixed in February.

The student who passes the ongoing test will take the final exam relating to the remaining part of the program.

The final grade will be the average of the two tests (ongoing test and final test).

If the student does not take or does not pass the ongoing test, he/she will take the final exam on the full-program.

The use of textbooks, notes, handouts is NOT permitted.

The use of ANY electronic device is NOT permitted during the exam.

Oral Test (Optional)

Students who have achieved a minimum score of 18/30 in the written test, and wish to integrate their grade, could be taken an oral exam.

The oral exam will be considered passed if the candidate has obtained an evaluation of at least 18/30.

The final grade will be a weighted average between the result of the written test and the oral exam, where the former will have a weight of 3/4, the latter of 1/4.

Teaching tools

PC equipped with touch screen and video projector. The slides and videos projected in class are available for download in the institutional repository of the University of Bologna.

Office hours

See the website of Andrea Gualandi