LIGHT-CAT Light-driven Catalytic Technologies for the Selective Functionalisation of C(sp3)-H Bonds

PRIN 2022 PNRR Melchiorre

Abstract

The LIGHT-CAT project aims to develop new sustainable catalytic strategies by merging visible-light photochemistry with modern catalytic platforms, including metal catalysis and organocatalysis. The goal is to design efficient and selective methods for the direct functionalisation of simple and abundant molecules, such as alkanes and natural products, with minimal environmental impact. By exploiting the power of visible light as a renewable energy source, the project will enable novel radical-based transformations through Hydrogen Atom Transfer (HAT) processes. These will allow direct activation of strong, otherwise inert, C(sp³)–H bonds, offering streamlined access to complex and valuable chemical structures. The project is carried out by a consortium of three teams: the University of Bologna (Paolo Melchiorre, project coordinator), the University of Pavia (Maurizio Fagnoni), and the University of Roma Tor Vergata (Massimo Bietti). Their complementary expertise in photochemistry, radical catalysis, and sustainable synthesis ensures a synergistic and interdisciplinary approach. The expected outcomes include the discovery of new light-driven catalytic processes, the development of more sustainable synthetic tools, and a deeper understanding of reaction mechanisms. LIGHT-CAT ultimately contributes to the advancement of green chemistry and the design of low-impact, innovative chemical technologies.

Dettagli del progetto

Responsabile scientifico: Paolo Melchiorre

Strutture Unibo coinvolte:
Dipartimento di Chimica Industriale "Toso Montanari"

Coordinatore:
ALMA MATER STUDIORUM - Università di Bologna(Italy)

Contributo totale di progetto: Euro (EUR) 234.553,00
Contributo totale Unibo: Euro (EUR) 141.916,00
Durata del progetto in mesi: 24
Data di inizio 30/11/2023
Data di fine: 30/11/2025

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