- Docente: Luca Bernardi
- Credits: 6
- SSD: CHIM/06
- Language: English
- Moduli: Luca Bernardi (Modulo 1) Letizia Sambri (Modulo 2)
- Teaching Mode: Traditional lectures (Modulo 1) Traditional lectures (Modulo 2)
- Campus: Bologna
- Corso: Second cycle degree programme (LM) in Low Carbon Technologies and Sustainable Chemistry (cod. 9246)
Learning outcomes
At the end of the course, the student is acquainted with the practice of green chemistry in the industrial synthesis of fine and commodity organic chemicals. Focusing on efficiency in organic synthesis, the student will know how to deal with the different aspects of this approach and ensuing applications. The student will be familiar with some of the natural products that have key roles in various areas of the chemical industry. The focus will be set on both mass intensive materials and structurally complex natural compounds of great medicinal/industrial utility. The student will know the structure, the properties, the industrial utilization and the biosynthetic pathways of these organic materials.
Course contents
-Background knowledge:
a basic understanding of organic chemistry, which is generally acquired in bachelor courses in chemistry and related disciplines, is required. In more detail:
-recognition of the main functional groups of small organic molecules, their reactivity and mechanistic implications.
-basic principles of catalysis and stereochemistry.
-selectivity in its different aspects (chemo-, regio- and stereoselectivity).
-basic principles of synthesis planning.
The main subjects treated in the course will be:
-Introduction to industrial organic chemistry: the main parameters to consider in scaling a laboratory synthesis to a plant process. Application to active pharmaceutical ingredients. Analysis of case studies from literature.
-Principles and mechanisms of catalytic processes intensively used in the fine and commodity chemical industries.
-Classification, properties and main manufacturing routes to some popular classes of fine chemicals (e.g. agrochemicals, sweeteners, fragrances, etc.).
Readings/Bibliography
Lectures handouts available via web at AlmaDL.
Teaching methods
Lectures assisted by videoprojections and/or blackboard drawings. Interactive training.
Assessment methods
Oral exam.
Teaching tools
Video projections and/or blackboard.
Office hours
See the website of Luca Bernardi
See the website of Letizia Sambri
SDGs
This teaching activity contributes to the achievement of the Sustainable Development Goals of the UN 2030 Agenda.