85149 - Molecular Physiology

Academic Year 2020/2021

  • Docente: Barbara Monti
  • Credits: 6
  • SSD: BIO/09
  • Language: Italian
  • Teaching Mode: Traditional lectures
  • Campus: Bologna
  • Corso: Second cycle degree programme (LM) in Health Biology (cod. 9212)

    Also valid for Second cycle degree programme (LM) in Molecular and cellular biology (cod. 8021)

Learning outcomes

At the end of the course the student has deepened inside the molecular mechanisms of cell physiology, including the response to hormones and to other cellular messengers, as well as of development and aging processes at the cellular, organ and body level.

Course contents

1. Physiopathological role of protein degradation mechanisms (proteasome and lysosomes) and autophagy.

2. Physiopathological cell deaths.

3. Physiopathological role of conventional and non-conventional cellular communication systems, in particular those mediated by vesicles and gases (nitrogen monoxide).

4. Molecular mechanisms at the basis of homeostatic integration systems: neuroendocrine regulation.

5. Gut-brain axis as a model of molecular interaction between the nervous system, the immune system and the digestive tract with the intestinal microbiota and its physiopathological role.

6. Molecular and cellular mechanisms regulating circadian rythm and its physiopathological role.

Readings/Bibliography

There are no textbooks available, but the lectures' presentations will be made available on IOL and specific review and research articles will be indicated to integrate the preparation at a more advanced level.

Teaching methods

Teaching methods include both frontal and flipped class-room lectures, in which students present scientific articles that are discussed with the class.

Assessment methods

Oral examination. Students are expected to present a scientific paper during the course. To this presentation it will be assigned a rating that is 50% of the final grade. At the end of the course, the oral examination will be an interview; to this inteview will be assigned a rating that will be the other half of the final grade. For the exam, each student can start from a chosen subject and then the examination will continue with the discussion on various topics of the course.

Teaching tools

The material utilized for lectures (power point presentation) will be made available to students on the IOL website. Reading and analysis of research article will be encouraged.

Office hours

See the website of Barbara Monti

SDGs

Good health and well-being Gender equality

This teaching activity contributes to the achievement of the Sustainable Development Goals of the UN 2030 Agenda.