- Docente: Marianna Penzo
- Credits: 2
- SSD: MED/05
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: First cycle degree programme (L) in Biomedical Laboratory techniques (cod. 8484)
Learning outcomes
At the end of the course students will have acquired the fundamental knowledge to critically evaluate and interpret the results of the more used diagnostic approaches in hepatic, cardiovascular and haemostasis pathologies.
Course contents
LABORATORY TESTING FOR IN SUPPORT OF THE DIAGNOSIS OF CARDIOVASCULAR DISEASE
Markers of lipid profile and hypertension for the determination of cardiovascular risk; markers of acute myocardial infarction
PRENATAL DIAGNOSTIC TESTS
Screening tests (Bi and Tri- tests); NIPT (non invasive prenatal testing)
STEM CELLS FROM CORD BLOOD
Stem cells, selection and donation, harvest, fields of use.
NEONATAL SCREENING
Principles and main application for phenylketonuria, congenital hypothyroidism, cystic fibrosis, widened screening.
GENETIC TESTING
Biochemical techniques (for cistic fibrosis, phenilketonuria, thalassemias), Molecular techniques: Indirect genetic tests (length polymorphisms, SNP); Direct genetic tests (known mutations search, unknown mutations search). Diagnostic applications, NGS, panels/clinical exome. NIPT (non invasive prenatal testing).
LIQUID BIOPSY AND CIRCULATING TUMOR MATERIAL SEARCH: CELLS, DNA, RNA
Teaching methods
Frontal classes, visualization of movies showing clinical laboratory testing, discussion of clinical cases.
Assessment methods
Oral examination.
The final mark of the integrated course Clinical Pathology II will be the average of the marks obtained in the exams of Applied Clinical Pathology, Genetic Clinical Pathology and Techniques of Clinical Pathology 2.
Teaching tools
pdf files used in support of teaching will be available online on IOL website.
Office hours
See the website of Marianna Penzo
SDGs
This teaching activity contributes to the achievement of the Sustainable Development Goals of the UN 2030 Agenda.