46193 - Pharmaceutical Technology

Learning outcomes

At the end of the course the student: - possesses the knowledge and skills relating to the preparation and formulation of the various conventional pharmaceutical forms and other aspects of pharmaceutical technology  and biopharmaceutics connected to the development of medicinal product, as well as the chemical-technological aspects connected to their industrial production; - possess the knowledge that allows understanding the logic behind the formulation of generic medicinal products and the evaluation of bioequivalence parameters; - possess the knowledge and skills relating to regulatory sciences with emphasis on the quality control of medicinal products.

Course contents

Introduction to medicinal products and dosage forms. Principles of biopharmaceutics.

Solid dosage forms. Powders. Granules and granulation. Tablets and compaction. Coating of tablets and multiparticulates. Hard and soft capsules. Suppositories and pessaries.

Liquid dosage forms. Interfacial phenomena. Properties of solutions, suspensions, emulsions. Syrups. Sterilization and sterile dosage forms. Parenterals. 

Semisolid dosage forms. Principles of rheology. Creams, ointments, gels and pastes. Vegetable drugs preparations.

Readings/Bibliography

P. Colombo et al., Principi di tecnologia farmaceutica, CEA, 2015.

M.E. Aulton et al., Tecnologie farmaceutiche: progettazione e allestimento dei medicinali. EDRA, 2015.

Teaching methods

Frontal instruction

Assessment methods

Oral exam on all the subjects discussed during the course.

Teaching tools

The material discussed and projected during the lessons will be avainabe in the app Virtuale.

Office hours

See the website of Paolo Blasi