90401 - General Pathology

Learning outcomes

This course aims to provide graduate with knowledge on the pathological bases of main human disorders.

Course contents

CELLULAR PATHOLOGY
-Etiology and pathogenesis
-Cellular adaptations: hyperplasia, atrophy, metaplasia
-Cell damage, autophagy, apoptosis and necrosis
DEFENSE MECHANISMS and IMMUNOLOGY
-Damage signals and the damage response
-Innate immune system
-Acute and chronic inflammation
-Systemic effects of inflammation, fever and thermoregulation
-Repair of wounds
-Hemostasis and coagulation cascade
-Adaptive immunity: B and T cells
- Vaccines
INFECTIOUS DISEASES
- Infectious Agents - Viruses
-Mechanisms of Infection - SARS-Cov-2
-Epidemiology and Diagnosis of Infections - SARS-Cov-2
-Prevention and Treatment of Infections - SARS-Cov-2
MOLECULAR BIOLOGY AND GENETIC PATHOLOGY
-Maintenance and transmission of genetic information
-DNA and RNA
-DNA mutations
-Genetic diseases
autosomal dominant inheritance
autosomal recessive inheritance
X-linked
- Chromosomal disorders
ONCOLOGY
-Characteristics of the tumor cell
-Neoplastic process
-Classification of tumors
-Molecular genetics of tumors, oncogenes and tumor suppressors
-Carcinogenic Agents
-HPV - Mechanisms of carcinogenesis
-HPV - Epidemiology and prevention

Readings/Bibliography

At the beginning of the integrated course (I.C.), students will receive indication on updated didactic materials produced in electronic format. These materials are stored on AMS Campus AlmaDL University of Bologna website: http://campus.unibo.it/ . Username and password are those given to each student of the University of Bologna.

Teaching methods

Ex-cathedra lessons and practices on computers

Assessment methods

Written final examination via true/false quiz

Teaching tools

Video (multimedial) and overhead projectors, computers and softwares. For slides, see AMS Campus.

Office hours

See the website of Paolo Garagnani