90316 - General Pathology Lab-based Course (C1)

Learning outcomes

The students will study the morphological changes caused by the disease processes and the basic reactions to etiologic agents in cells and tissues, together with the pathogenetic mechanism of their development. This educational laboratory will enable the student to recognize the microscopic alterations in cells and tissues characteristic of the pathologic processes, by the study of general histopathology which will be hold in parallel to the course of General Pathology and Physiopathology.

Course contents

1. Cellular and extracellular pathology: reversible cell injury and fatty change, amyloidosis, necrosis and infarction.

2. Neoplastic transformation: benign tumors, malignant tumors, metastases.

3. Inflammatoryand reparative response: acute inflammation, chronic nonspecific and granulomatous inflammation, granulation tissue, sclerosis, cirrhosis.

4. Vascular disease: medial calcific artheriosclerosis, atherosclerosis, thrombosis.

Readings/Bibliography

Web site:

http://virtualmicroscopy.patologia-sperimentale.unibo.it/ [http://patologia-sperimentale.unibo.it/virtualmicroscopy/]

https://unibo.smartzoom.com/

V. Kumar, A.K. Abbas, J.C. Aster. “Robbins e Cotran - Le basi patologiche delle malattie”, 9a edizione, 2015, Casa Editrice Edra, Milano

Teaching methods

This course is included in the Teaching Innovation Project of University of Bologna.

Lessons will be held in blended teaching mode:

- 22 hours of lessons in computer room for the analysis of digitized histopathological slides under the guidance of a teacher, who will addrss the study and provide all the necessary explanations.

- 12 hours of on-line lessons, using Teams, Virtual and the digital platforms for managing virtual slides (virtual microscopy, Smartzoom and Olyvia). Students will have to recognize the histopathological features of the virtual slides in flipped-classroom (problem solving).

- Students will also have access h 24 to the Virtual Microscopy platform containing: digital slides at different magnifications, explanatory texts, hypertext links and markers. In addition, self-evaluation tests are available for students.

Assessment methods

The learning level will be assessed at the end of classes. The examination includes a practical microscopy test to assess the learning of the General Pathology Laboratory.

The exam aims to evaluate the knowledge acquired by the student on the course contents in order to achieve the educational goals. The exam assesses the student ability to frame the topic of general pathology or pathophysiology on which they are questioned and to expose it by making the necessary logical-deductive connections. The coherence of the conceptual succession and the appropriateness of the scientific language are further elements of evaluation. The examination of the General Pathology and Pathophysiology Course includes the observation and oral description of a microscopic preparation up to the recognition of the specific histopathological picture. The student must be able to discuss the morphological alterations of a histopathological specimen, in relation to the theoretical and practical knowledge acquired on the subject during the course.

Graduation of the final grade

18-20: knowledge of the basic concepts without serious gaps. Exposition of concepts and language as a whole acceptable.

21-25: knowledge of the basic concepts without gaps. Ability to analyze and link in partial autonomy. Exposure of discrete concepts and language.

26-29: preparation of good or very good level or even excellent preparation but with inaccuracies in the presentation that compromise the achievement of full marks. Ability to analyze and link independently. Exposure of concepts in the right succession and mastery of the language.

30-30L: full preparation, consolidated and without inaccuracies on the topics covered in the course. Ability to promptly frame the topic. Ability to analyze and connect independently. Concepts in the right succession and full command of the specific language.

The final grade derives from the collegial evaluation carried out by all the teachers of General Pathology and Physiopathology Integrated Course.

Office hours

See the website of Letizia Polito