08956 - Clinical Biochemistry

Academic Year 2022/2023

  • Docente: Stefania Evangelisti
  • Credits: 1
  • SSD: BIO/12
  • Language: Italian
  • Teaching Mode: Traditional lectures
  • Campus: Bologna
  • Corso: First cycle degree programme (L) in Nursing (cod. 5907)

Learning outcomes

The student, at the end of the module, thanks to the knowledge of the fundamental principles of chemistry and organic molecules of biological interest, is able to evaluate biological and biochemical parameters in biological samples and in vivo, also in relation to pathophysiological states, at different levels of structural organization, from single molecules to cells, tissues, organs, up to the whole organism.

Course contents

  • Introduction to the course
  • In vivo and ex vivo clinical biochemistry in the context of laboratory medicine.
  • The role of laboratory medicine in the clinical context.
  • Elements of organization of a biomedical laboratory
  • Reference values and decision levels.
  • Performance of a diagnostic test: sensitivity, specificity, predictive value
  • The pre-analytical, analytical and post-analytical phases of laboratory investigations.
  • Biological, pre-analytical and analytical variability.
  • Clinical indications, contraindications, side effects and complications.
  • Types of laboratory tests: routine, urgency, emergency.
  • Screening tests
  • From the patient to the laboratory test: patient preparation, collection, treatment and storage of samples
  • Examples of the role of the nurse in the classification of muscular disorders, in the laboratory diagnostics of the cerebrospinal fluid, in molecular diagnostics in vivo.

Readings/Bibliography

  • Teaching materials in pdf
  • M. Ciaccio e G. Lippi, Biochimica Clinica e Medicina di Laboratorio, EDISES

Teaching methods

Lectures with powerpoint presentations

Assessment methods

The level of learning will be verified at the end of the course through a test with multiple choice questions, carried out on the computer, aimed at ascertaining the student's knowledge of all the topics of the integrated course.

The test consists of 31 questions. Each question has 4 answers, only one of which is correct. Each correct answer is worth one point.
Whoever reaches a minimum of 18 points passes the test. The number of correct answers, if greater than or equal to 18, corresponds to the final grade. With 31 correct answers the final mark is 30 cum laude.

Teaching tools

Didactic materials in power point presentations.

Office hours

See the website of Stefania Evangelisti