08956 - Clinical Biochemistry

Academic Year 2022/2023

  • Docente: Stefania Evangelisti
  • Credits: 1
  • SSD: BIO/12
  • Language: Italian
  • Teaching Mode: Traditional lectures
  • Campus: Rimini
  • Corso: First cycle degree programme (L) in Nursing (cod. 8475)

Learning outcomes

The student, at the end of the module, thanks to the knowledge of the fundamental principles of chemistry and organic molecules of biological interest, is able to evaluate biological and biochemical parameters in biological samples and in vivo, also in relation to pathophysiological states, at different levels of structural organization, from single molecules to cells, tissues, organs, up to the whole organism.

Course contents

  • Introduction to the course
  • In vivo and ex vivo clinical biochemistry in the context of laboratory medicine.
  • The role of laboratory medicine in the clinical context.
  • Elements of organization of a biomedical laboratory
  • Reference values and decision levels.
  • Performance of a diagnostic test: sensitivity, specificity, predictive value
  • The pre-analytical, analytical and post-analytical phases of laboratory investigations.
  • Biological, pre-analytical and analytical variability.
  • Clinical indications, contraindications, side effects and complications.
  • Types of laboratory tests: routine, urgency, emergency.
  • Screening tests
  • From the patient to the laboratory test: patient preparation, collection, treatment and storage of samples
  • Examples of the role of the nurse in the classification of muscular disorders, in the laboratory diagnostics of the cerebrospinal fluid, in molecular diagnostics in vivo.

Readings/Bibliography

  • Teaching materials in pdf
  • M. Ciaccio e G. Lippi, Biochimica Clinica e Medicina di Laboratorio, EDISES

Teaching methods

Lectures with powerpoint presentations

Assessment methods

The evaluation of the knowledge acquired by the students is based on an single written exam for the Integrated Course of Pathological Sciences consisting of 60 questions with multiple choice (30 questions regarding the teaching of Pathology and Immunology, 10 questions for Clinical Pathology, 10 questions for Clinical Biochemistry and 10 questions for General Pharmacology). The total time allowed for the examination is 50 minutes. The test is considered passed positively from 37 correct answers, corresponding to 18/30 vote.

Teaching tools

Didactic materials in power point presentations.

Office hours

See the website of Stefania Evangelisti