- Docente: Luca Morandi
- Credits: 1
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: Single cycle degree programme (LMCU) in Medicine and Surgery (cod. 8415)
Learning outcomes
Describe the clinical biochemistry skills and techniques to evaluate the functional state of organs and tissues, using liquid and solid samples from patients.
Course contents
- Course introduction
- Clinical biochemistry
- Biomarkers
- Laboratory medicine: the pre-analytical, analytical and post-analytical phases
- Variability and standardization of laboratory testing
- Performance of a laboratory test: sensibility, specificity, predicting values and ROC curves
- Principle of epigenetics
- The use of genetic and epigenetic biomarkers in oncology and neurological disorders
- The assessment of diagnostic and prognostic tests with examples from new assays based on Next Generation Sequencing for head and neck carcinomas
- Personalized medicine: liquid biopsy to monitor the evolution of the cancer genome through a minimally invasive technique
- Bioinformatic tools for Next Generation Sequencing analysis
- Cerebrospinal fluid analysis in the central nervous system diseases
Readings/Bibliography
Files will be provided by IOL platform (.pdf slides, video, reference papers)
Teaching methods
Lectures
Assessment methods
Final evaluation will be performed by means of a joint test on all topics covered in the integrated course. The test will be based on oral examination with two questions concerning two randomly selected modules. The student may ask for an additional question about the remaining module. The final score will be the average calculated from the two or three answers provided.
Teaching tools
Power point presentations, video, assessment tests using .quizizz platform
Office hours
See the website of Luca Morandi