- Docente: Uberto Pagotto
- Credits: 4
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: Single cycle degree programme (LMCU) in Medicine and Surgery (cod. 8415)
Learning outcomes
The learning outcomes are the following: 1) understanding the phyiological basis of the hormone secretion and of the growth of the endocrine cells; 2) understanding the basis of the hormonal hyper and hyposecretion and of the pathological growth of the endocrine tumors including sporadic and familial tumors, to generate diagnois and appropriate therapy 3) understanding the pathogenetic mechanisms leading to the development and maintenance of metabolic diseases as obesity, gout, hyperlipidaemias and diabetes; 4) understanding the pathogenetic mechanisms leading to the development and maintenance of bone metabolic diseases as osteoprosis, hypercalciuria and Paget; 5) critically reading and knowing scientific literature in the field of endocrinology and metabolism 6) critically applying the current knowledgement to a more tailored approach to the diagnosis and therapy of endocrinological patients
Course contents
1) The endocrine system: introduction, hormone classification,
hormone resistance 2) Hyophalamic-pituitary diseases: hyper and
hypopituitarism, pituitary adenomas, endocrine evaluation of
pituitary axes.
3) Thyroid diseases: thyroid nodule, goiter, thyroid
carcinomas, thyroiditis, hyper and
hypothyroidism. endocrine evaluation of thyroid function
4) Parathyroid diseases, alterations of calcium metabolism, hyper
and hypoparathyroidism, osteoporosis
5) Metabolic bone diseases: Paget
6) Adrenal diseases: congenital adrenal hyperplasia, hypo and
hypercorticism, adrenal incidentalomas, pheocromocytomas,endocrine
evaluation of adrenal function
7) Endocrine hypertension: hyperladosteronisms.
8) Male hypogonadism, infertility and erectile dysfunction.
Endocrine evaluation of the testis. Klinefelter syndrome.
9) Ovary diseases: polycystic ovary syndrome. Endocrine evaluation
of the ovary.
10) Turner syndrome.
11) Neuroendocrine tumors MEN-1 e MEN-2
12) Growth defects, alterations of the puberty
13) Polyendocrinopathies, paraneoplastci
syndrome (SIADH).
14) Diabetes insipidus 15) Type 1 and 2 diabetes mellitus. Acute
and chronic alterations associated to
diabetes. Hypoglycaemia.
16) Alterations of lipid metabolism
17) Gout 18) Fodd intake control. Adipose tissue distribution and
function. Monogenic cuases of obesity. Endocrione causes of
obesity. Metabolic syndrome. Binge eating disorders,
Anorexia.
For all topics, notions about therapy is
included
Readings/Bibliography
Books suggested:
(1) Lenzi, Lombardi, Martino, Vigneri. Endocrinologia
Clinica. Ed Minerva Medica
(2) Williams Textbook of Endocrinology
(3) Faglia G, Beck-Peccoz P. Malattie del sistema endocrino e del
metabolismo. 4a Edizione. The McGraw-Hill Comp.
(4) Endocrinologia Clinica di Ziliotto D - Piccin-Nuova
Libraria
(5) Endocrinologia Clinica di Monaco F. Società Editrice
Universo
(6) Camanni F., Ghigo E. Malattie del sistema endocrino e del
metabolismo Ed. Edi-Ermes 4° Edizione
Teaching methods
The course in Endocrinology and Metabolism is composed by frontal oral lectures with presentation of some depicted clinical cases.
At the end of each lecture the slides presented during the lecture will be given in the ppt format. The whole set of slides represents the basis to prepare the exam, however an integration with a textbook is warmly suggested. For the title of the books suggested see "TEXT" session.
Assessment methods
The assessment is oral in front of a commission composed by Prof Bazzoli, Prof. Festi and collaborators for the Gastroenterology part and by Dr. Pagotto and collaborators for the Endocrinology and Metabolism parts.
The final note derives from the median of the two single notes obtained in Gastroenterology and Endocrinology.
Teaching tools
Lecture slides and textbook.
Office hours
See the website of Uberto Pagotto