- Docente: Anna Tinti
- Credits: 9
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: Single cycle degree programme (LMCU) in Medicine and Surgery (cod. 8415)
Course contents
Transition metals, complexes ions.
Chemical reactions. Chemical equations. Balancing chemical equations; Lavoisier law. Mole definition (gram-atomic, gram-molecular, gram-formula weight). Chemical reactions and stoichiometry.
Types of chemical reactions. Oxidation state. Redox reactions. Electrochemical cells and standard reduction potentials: electrochimical series. Nernst's equation. Spontaneity criteria for redox reactions. Standard potentials in biochemistry.
Solutions. Electrolytic and not electrolytic solutions. Expressing concentration of solutions. Colligative properties. Raoult's law. Boiling point elevation and freezing point depression. Osmotic pressure of a solution: biological importance.
Reaction kynetics: reaction rate. Effective collisions and activated complex theories. Energy diagram for a chemical reaction. Rate laws and reaction order. Reaction mechanisms: elementary and multistage reactions. Half-life period. Arrhenius equation. Catalysts.
Chemical equilibrium. Equilibrium constants. Factors influencing the chemical equilibrium. Le Chatelier's principle. Chemical equilibrium for heterogeneous systems.
Self-ionization of water and its dissociation equilibrium constant, Kw. Acid, basic and neutral solutions. The pH concept; pH scale. Ionic equilibria in aqueous solution: acids and bases. Acid-base Arrhenius theory. Acid-base Brönsted and Lowry theory. Dissociation equilibria of weak acids and bases: acid and base dissociation constants. Polyprotic acids. Hydrolysis. Buffer solutions and Henderson-Hasselbalch equation. Biological buffers. pH of ampholythe solutions. Stiochiometric calculations. Acid-base Lewis theory. pH measurements. Indicators. Acid-base titrations.
Dissociation equilibria of scarcely soluble electrolytes: solubility products. Kps-solubility relationships. Common-ion effect.
Readings/Bibliography
K.J. Denniston, J.J. Topping, R.L. Caret; Chimica Generale, Chimica Organica, Propedeutica Biochimica; Edizione italiana, McGraw-Hill, 2012
Teaching methods
Assessment methods
Written exam on the following modules: Chemistry (4 credits) and
General Biochemistry (5 credits).
Teaching tools
Office hours
See the website of Anna Tinti