88266 - HUMAN ADAPTIVE INTERACTIONS TO CHANGING ENVIRONMENTS

Conoscenze e abilità da conseguire

At the end of the course, students will acquire knowledge on the distribution of human biodiversity all over the world and on the main adaptive processes that have influenced it by shaping patterns of phenotypic and molecular variation of human populations. In particular, it will be explored how the occupation of different and changing environments by modern humans has prompted ecological and cultural shifts that introduced novel selective pressures impacting on the human genome. Moreover, special attention will be deserved to the discussion of cases in which ecological and cultural contexts have changed so rapidly in the modern era to trigger adaptive traits previously shaped by natural selection into maladaptive ones. Accordingly, the course will also provide to the students elements useful for the understanding of the evolutionary causes of differential susceptibilities of human populations to complex diseases.

Contenuti

The course will present the main theoretical models developed so far to describe the processes by which human populations have biologically adapted to a variety of environmental conditions. Morevoer, it will describe patterns of molecular and phenotypic variation that underlie some of the most well-studied human adaptive traits. Finally, evidence supporting dis-adaptive processes undergone by present-day human populations due to rapid changes occurred in their environmental and/or cultural contexts will be presented.

The course contents will be organized according to the following arguments:

1. Introduction to evolutionary principles

2. Processes enabling human biological adaptation to environmental settings

3. Contextualization of human adaptive traits in the overall landascape of human biodiversity

4. Case studies describing adaptive processes of human populations in response to environmental stresses

5. Case studies describing dis-adaptive processes of human populations due to rapid environmental/cultural changes

Testi/Bibliografia

Scientific articles and review papers focused on the main arguments discussed during the course will be shared with the students by means of dedicated tools (e.g. Virtuale).

For students who want to further deepen some topics the following book is suggested:

Jobling, Hollox, Hurles, Kivisild, Tyler-Smith. 2014. Human Evolutionary Genetics (II edition). Garland Science, Taylor & Francis Group.

Metodi didattici

Lectures and seminars are scheduled.

Students with learning disorders and\or temporary or permanent disabilities: please, contact the office responsible (https://site.unibo.it/studenti-con-disabilita-e-dsa/en/for-students) as soon as possible so that they can propose acceptable adjustments. The request for adaptation must be submitted in advance (15 days before the exam date) to the lecturer, who will assess the appropriateness of the adjustments, taking into account the teaching objectives.

Modalità di verifica e valutazione dell'apprendimento

The mark will be obtained by means of a one-hour written exam made up of a combination of multiple-choice (9, each one accounting for maximum 3 points) and open questions (1, accounting for maximum 3 points and considered for awarding Lode).

Strumenti a supporto della didattica

Slides of the lectures and scientific papers will be shared with the students by means of dedicated tools (e.g. Virtuale)

Orario di ricevimento

Consulta il sito web di Marco Sazzini