90932 - BIOMOLECULAR BASIS OF ANATOMICAL PATHOLOGY

Anno Accademico 2023/2024

  • Docente: Giovanna Cenacchi
  • Crediti formativi:: 6
  • SSD: MED/08
  • Lingua di insegnamento: Inglese
  • Moduli: Giovanna Cenacchi (Modulo 1) Giovanna Cenacchi (Modulo 2)
  • Modalità didattica: Convenzionale - Lezioni in presenza (Modulo 1) Convenzionale - Lezioni in presenza (Modulo 2)
  • Campus: Bologna
  • Corso: Laurea Magistrale in Medical Biotechnology (cod. 9081)

Conoscenze e abilità da conseguire

Discuss the principal epidemiologic, morphologic, phenotypic, clinicopathologic features, and etiopathogenesis of common neoplastic and non neoplastic disorders, focusing on cardiovascular and neuromuscolar disorders. Describe the methods used to process and analyze tissue samples for diagnostic Anatomic Pathology, including histopathology and ultrastructural laboratory instrumentation and devices. Discuss innovative technologies for early diagnosis of disease, and for the identification of new molecular targets for tumor therapies.

Contenuti

  • definition of Pathological Anatomy
  • Methods and Techniques in Pathological Anatomy
  • Tumor classification
  • malignant Tumor of Thyroid
  • SNC tumor classification
  • Molecular aspects of SNC Tumor
  • Pathogenetic mechanism of ischemic myocardium disease
  • Neuromuscular disease: muscle pathology
  • Methods and techniques in muscle pathology diagnostics
  • Elementary lesions of glomerular diseases
  • Electron microscopy : Transmission and scanning electron microscopes
  • Protocols in sample preparation for ultrastructural diagnosis
  • Ultrastructural markers in Tumor diagnosis
  • Case study
  • Student working groups about main diagnostic issues
  • The Course is completed by 1 CFU of practical activity in the Laboratory at Laboratorio di Morfologia (FABIT). Specific muscle disease cases will be directly studied and analyzed at light microscopy (30 microscopes are available) and discussed in student group and in a plenary session guided by both the teacher and tutor


    Testi/Bibliografia

    Kumar, Cotran, Robbins "Basic Pathology", Saunders eds

    Metodi didattici

    conventional lectures and student workig group

    case study

    practical laboratory activity (Laboratorio di Morfologia, FABIT)


    Modalità di verifica e valutazione dell'apprendimento

    the student will be evaluated after oral examination about:

    1. general aspect of pathological Anatomy (techniques and methodology)
    2. specific pathology (morphological, Ultrastructural and molecular aspect of main human diseases)
    3. Discussion on ultrastructural micrograph.

    Final vote is the media value obtained by each question (1, 2 and 3) vote


    Strumenti a supporto della didattica

    Ex -cathedra teaching, conventional

    Student working Group about main diagnostic issues

    Case study and plenary discussion


    Orario di ricevimento

    Consulta il sito web di Giovanna Cenacchi

    SDGs

    Istruzione di qualità

    L'insegnamento contribuisce al perseguimento degli Obiettivi di Sviluppo Sostenibile dell'Agenda 2030 dell'ONU.