88380 - SUSTAINABLE AND NATURAL MATERIAL-DERIVED ORGANIC PROCESSES

Conoscenze e abilità da conseguire

At the end of the course, the student is acquainted with the practice of green chemistry in the industrial synthesis of fine and commodity organic chemicals. Focusing on efficiency in organic synthesis, the student will know how to deal with the different aspects of this approach and ensuing applications. The student will be familiar with some of the natural products that have key roles in various areas of the chemical industry. The focus will be set on both mass intensive materials and structurally complex natural compounds of great medicinal/industrial utility. The student will know the structure, the properties, the industrial utilization and the biosynthetic pathways of these organic materials.

Contenuti

-Background knowledge:

a basic understanding of organic chemistry, which is generally acquired in bachelor courses in chemistry and related disciplines, is required. In more detail:

-recognition of the main functional groups of small organic molecules, their reactivity and mechanistic implications.

-basic principles of catalysis and stereochemistry.

-selectivity in its different aspects (chemo-, regio- and stereoselectivity).

-basic principles of synthesis planning.

The main subjects treated in the course will be:

-Introduction to industrial organic chemistry: the main parameters to consider in scaling a laboratory synthesis to a plant process. Application to active pharmaceutical ingredients. Analysis of case studies from literature.

-Principles and mechanisms of catalytic processes intensively used in the fine and commodity chemical industries.

-Classification, properties and main manufacturing routes to some popular classes of fine chemicals (e.g. agrochemicals, sweeteners, fragrances, etc.).

Testi/Bibliografia

Lectures handouts available via web at AlmaDL.

Metodi didattici

Lectures assisted by videoprojections and/or blackboard drawings. Interactive training.

Modalità di verifica e valutazione dell'apprendimento

Oral exam.

Strumenti a supporto della didattica

Video projections and/or blackboard.

Orario di ricevimento

Consulta il sito web di Luca Bernardi

Consulta il sito web di Letizia Sambri