07732 - Clinical Pathology

Learning outcomes

At the end of the course the student: - has learned the theoretical and methodological bases in cytology, cytopathology, immunohematology and genetic pathology and the application of cellular and molecular methodologies to the diagnostic procedure in human pathology. - is able to interpret the meaning of the results of the laboratory diagnostic investigations described above in the diagnostic characterization of the major human pathologies.

Course contents

Module 1

- interpretation of laboratory tests

- Neonatal screening test: principles and main applications

- Blood cell count and laboratory evaluation of anemia

- Tests for the evaluation of the haemostatic function

- Laboratory tests in transfusion medicine

- Definition of Genetic tests

- Biochemical techniques (for cystic fibrosis, phenylketonuria, thalassemia)

- Diagnostic Molecular techniques:

- Indirect genetic tests: length polymorphisms, SNP,
- Direct genetic tests:
Techniques for the search for known mutations,
Techniques for the search for unknown mutations

Module 2

- Urine and renal function analysis

- Laboratory tests for liver function

- Evaluation of serum proteins

- Humoral tumor markers (traditional and innovative)

- Precision medicine

- Liquid biopsy

 

Teaching methods

teaching lessons, lab practice

Assessment methods

joint final oral examination. During the verification, at least two topics will be examined. At least two different topics will be discussed.

Teaching tools

Students receive the files of the presentations shown during the teaching lessons

Office hours

See the website of Lorenzo Montanaro

See the website of Michelangelo Fiorentino