Scheda insegnamento

  • Docente Claudio Trombini

  • Moduli Claudio Trombini (Modulo 1)
    Pier Giorgio Cozzi (Modulo 2)
    (Modulo 3)

  • Crediti formativi 6

  • SSD CHIM/06

  • Modalità didattica Convenzionale - Lezioni in presenza (Modulo 1)
    Convenzionale - Lezioni in presenza (Modulo 2)
    Convenzionale - Lezioni in presenza (Modulo 3)

  • Lingua di insegnamento Inglese

Anno Accademico 2017/2018

Conoscenze e abilità da conseguire

At the end of the course the student will know the concerns deriving from the incorrect production and use of chemicals; the student will learn which are the most safe and green alternative solvents and which innovative and safer synthetic strategies and protocols can be applied for the preparation of chemical substances in a more sustainable way. Among the innovative processes, he/she will be specially aware of nanomanifacturing.


  • The solvent global business. main applications in every day use products and in chemical industry. Role of solvents in chemical processes. Safety, health and environmental properties (SHE). Incremental optimization of known solvents and search for new reaction media.
  • Solvents-less reactions as solutions of the solvent issue. Solid-phase synthesis: sonochemistry and microwaves.
  • Water as solvent: chemical compatibility, solvation effects and dissolution of polar and apolar compounds. Use of surfactants, micelles as reaction media.
  • Supercritical fluids. properties of scWater: special use in the oxidation of watsres, including chemical weapons. ScCO2 as a reaction medium, an extractant and an eluent in analytical and preparative chromatography.
  • Ionic liquids: preparation and physical properties. Solvents by design: properties tunable by a proper choice of the anion and cation. Applications in organic synthesis. Applications in extractive chemistry, electroplating, and others.
  • Concluding remarks: a summary of the topics covered in this module. Guidelines for the preparatioon of the final report. Delivery of review articles to each student, individually


Lessons slides availbale for download. 

Reference book: F.M.Kerton, R.Marriott, "Alternative Solvents for Green Chemistry", RSC PUblishing, 2013

Metodi didattici

Lectures with multimedia support. Slides are available for download.

Modalità di verifica dell'apprendimento

A report is prepared by the student within 45 days after the completion of the course. In particular: one review article is provided to each student. On the basis of this reference materials the student has to follow this flow chart:

1) describe the general aspects of his/her assigned topic, e.g. ionic liquids, solid state chemistry, ultrasound assisted process, supercritical fluid, etc. This section should be limited to 500-1000 words, except for figures.

2) select an application of your choosing in the review article provided. Find the original paper which reports the application you have chosen.

3) describe the process or reaction reported. If a new solvent is used, collect information on its properties from the literature

4) analyze the proposed solution based on the use of a eco-friendly solvent or process,

5) compare the new process with the older one,

6) critically analyze pro's and con's of the proposed solution.

Sections 3-6 should be limited to no more than 3.000 words.

Strumenti a supporto della didattica

Multimedia supported lectures.

Orario di ricevimento

Consulta il sito web di Claudio Trombini

Consulta il sito web di Pier Giorgio Cozzi

Consulta il sito web di