| Academic Year | 2020-2021 |
|---|---|
| Subject area | Medical, Pharmaceutical and Veterinary Medical Sciences |
| Cycle | 36 |
| Coordinator | Prof.ssa Manuela Ferracin |
| Language | English, Italian |
| Duration | 3 years |
| Positions | 30 positions. More information in the PhD Programme Table. |
| Application deadline | May 21, 2020 at 01:00 PM (Expired) |
| Enrolment period | From Jul 10, 2020 to Jul 20, 2020 |
| Doctoral programme start date | Nov 01, 2020 |
- Operating centre
- Bologna
- Main Department
-
Department of Experimental, Diagnostic and Specialty Medicine - DIMES
- Associated Departments
-
Department of Medical and Surgical Sciences - DIMECDepartment of Biomedical and Neuromotor Sciences - DIBINEM
- Mobility abroad
- 3 months
- Research topics
- Solid and hematological neoplasms.
- Immunoprevention and immunotherapy of tumors.
- Oncology, genomics, proteomics and targeted therapy of musculoskeletal sarcomas.
- Development of new therapies, biological and cellular therapies in paediatric onco-hematology (neuroblastoma, acute myeloid leukaemia, leukaemias and lymphomas of B cells).
- Radiotherapy, oncological radiodiagnostics, radiomics and radiobiology.
- Rare tumors.
- ERBB family receptors.
- Resistance to targeted therapies.
- Acute and chronic myeloproliferative syndromes.
- Lympho(immuno) proliferative diseases, monoclonal gammopathies and multiple myeloma.
- Molecular basis, genetic studies, and development of innovative and targeted drugs against adult oncohemopathies (acute and chronic leukaemias, lymphomas and multiple myeloma).
- Molecular pathology of infections associated with implants: search of virulence factors of opportunistic microorganisms as etiologic agents of periprosthetic infections and pathogenic mechanisms.
- Plant toxins with N-glycosilase activity: mechanisms of cytotoxicity and immunotargeting.
- Alterations of protein glycosylation in pathological processes.
- Changes in ribosome biogenesis, cell proliferation and tumorigenesis.
- Immunology, genetics and epigenetics of aging, longevity and age-associated diseases.
- Allelic polymorphisms to identify risk factors associated with dementia and Alzheimer disease.
- Chronic pain.
- Omic data analysis.
- Genetic and epigenetic alterations as cancer diagnostic or prognostic biomarkers.
- Role of non-coding RNA in human cancer.
- Shiga toxin and hemolytic uremic syndrome.
- Human genomics and transcriptomics in normal conditions and in genetic disorders.
- Stem cells, differentiation and development.
- Nutrition, microbiota and cancer.
- Job opportunities and potential areas of employment
- Our PhDs find employment in public and private research institutions, both national and international (mainly European and U.S.), in the healthcare system, including national research and care institutes (IRCCS) and in private laboratories and clinics.
- Admission Board
-
Surname Name University Role email Ferracin Manuela Università di Bologna Member manuela.ferracin@unibo.it Pession Andrea Università di Bologna Member andrea.pession@unibo.it Zamagni Elena Università di Bologna Member e.zamagni@unibo.it Ardizzoni Andrea Università di Bologna Substitute andrea.ardizzoni2@unibo.it Bolognesi Andrea Università di Bologna Substitute andrea.bolognesi@unibo.it Cavo Michele Università di Bologna Substitute michele.cavo@unibo.it Dall'Olio Fabio Università di Bologna Substitute fabio.dallolio@unibo.it Amichetti Maurizio (maurizio.amichetti@apss.tn.it) for ASSP - Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento shall take part in the work of the Admission Board as Expert Member.
- Learning outcomes
- The learning goals of the PhD programme are as follows:
- We develop graduates with advanced knowledge of literature and theory in the fields of Oncology, Hematology and Pathology.
- We develop graduates with theoretical and practical knowledge of advanced research skills.
- We develop graduates capable of producing original research of quality appropriate for publication in high-impact scholarly journals.
- We develop graduates capable of producing translational research that applies to clinical challenges the advanced knowledge originating from laboratory research. - Activities to be carried out by Doctoral candidates
- The activity is largely devoted to translational and clinical research in the fields of oncology, hemathology and pathology. The activities include research in the laboratory, field research, clinical research, and the use of large advanced equipment in the field of molecular biology and genetics. The PhD program therefore directs towards preclinical and clinical research applications and offers wide opportunities to trainees to develop their activities in centers of scientific and clinical excellence.
- Research training activities compliant with the Doctoral programme's learning outcomes
- The PhD programme includes laboratory and/or clinical research activities, organized by the Supervisor of each PhD student, and teaching activities organized by three.
- The pool of medical PhD Programmes organizes courses of scientific English (24 hours, in collaboration with Centro Linguistico d'Ateneo) and courses on safety in the biomedical environment (12 hours, in collaboration with the Area Persone e Organizzazione of the University and with the safety managers of the medical Departments).
- The PhD programme organizes seminars by faculty members. Main subjects are: Biology and pathology of the cell cycle, Cell death and apoptosis, Mechanisms of cytotoxicity of Ribosome Inactivating Proteins, Genetic variants involved in longevity or age-associated diseases, Cytokines in human disease, Glycobiology and glycopathology, Molecular and cellular oncology, Carcinogenesis, Tumor immunology and immunotherapy, Diagnosis of hematopoietic and solid tumors, Cancer epidemiology and prevention, Conventional and innovative therapy of tumors, Biopathology and treatment of lymphomas, myeloma and acute leukaemias, Allogeneic/autologous stem cells transplantation, New molecular technologies for the study of hematologic malignancies. Role of non-coding RNAs in cancer.
- Each Supervisor coordinates the attendance of specific events (meetings, workshops, grand rounds, etc.) and provides advanced bioinformatical education and tools in relation to the specific research project of each PhD student. - Internationalization features
- - International experience. All PhD students must attend research laboratories abroad in major research institutions, for at least 3 months.
- Attraction of foreign graduates (5 Marie Curie at present). - Expected research results and products
- Papers published in international journals, indexed in PubMed (at least one full paper per PhD student during the PhD course, or within 2 years after the end of PhD), and oral/poster communications at national and international scientific meetings. Also, patents resulting from translational research and clinical protocols resulting from clinical research.
- Doctoral programme Academic Board
Surname Name University/Institution Qualification Arciola Carla Renata Università di Bologna Professore Associato Confermato Ardizzoni Andrea Università di Bologna Professore Ordinario Bolognesi Andrea Università di Bologna Professore Associato Confermato Brandi Giovanni Università di Bologna Professore Associato Confermato Brigotti Maurizio Università di Bologna Ricercatore Confermato Cavo Michele Università di Bologna Professore Ordinario Dall'Olio Fabio Università di Bologna Professore Associato Confermato Donati Davide Maria Università di Bologna Professore Associato Ferracin Manuela Università di Bologna Professore Associato Foschini Maria Pia Università di Bologna Professore Ordinario Garagnani Paolo Università di Bologna Professore Associato Lauriola Mattia Università di Bologna Ricercatore A Tempo Determinato - Art.24 Co.3 Lett. B) - L.240/2010 Lollini Pier Luigi Università di Bologna Professore Ordinario Masetti Riccardo Università di Bologna Ricercatore A Tempo Determinato - Art.24 Co.3 Lett. B) - L.240/2010 Montanaro Lorenzo Università di Bologna Professore Associato Confermato Morganti Alessio Giuseppe Università di Bologna Professore Ordinario Nanni Patrizia Università di Bologna Professore Associato Confermato Pantaleo Maria Abbondanza Università di Bologna Professore Associato Pelleri Maria Chiara Università di Bologna Ricercatore A Tempo Determinato - Art.24 Co. 3 Lett. B) - L.240/2010 Pession Andrea Università di Bologna Professore Ordinario Salvioli Stefano Università di Bologna Professore Associato Soverini Simona Università di Bologna Ricercatore Confermato Zamagni Elena Università di Bologna Ricercatore Confermato Zinzani Pier Luigi Università di Bologna Professore Ordinario
See also
- AMS phD thesis (in Italian) Published