- Docente: Giovanni Perini
- Credits: 6
- SSD: BIO/18
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: Second cycle degree programme (LM) in Molecular and cellular biology (cod. 8021)
Learning outcomes
Students will acquire notions about the basic molecular mechanisms
responsible for epigenetic phenomena with a spcial emphasis
on X-chromosme inactivation, allelic exclusion and DNA methylation
dynamics during embryogenesis
Course contents
Lectures will deal with the following subject matters: X-chromosome
inactivation, Genomic imprinting, Allelic exclusion, paramutation
in plants, RNA interference, chromatin organization, DNA
methylation dynamics during embryogenesis, HSP90 buffering.
Readings/Bibliography
Scientific papers from top ranked journals such as Cell, Science, and Nature.
Teaching methods
Standard lectures and paper-reading
Assessment methods
Oral exam focusing on the general expects of the epigenetics
phenomena, with a special attention on two paper articles to be
chosen among those discussed in class.
Teaching tools
Slides and papers from scientific journals
Office hours
See the website of Giovanni Perini