07732 - Clinical Pathology

Course Unit Page

SDGs

This teaching activity contributes to the achievement of the Sustainable Development Goals of the UN 2030 Agenda.

Good health and well-being

Academic Year 2021/2022

Learning outcomes

At the end of the course the student: - learned the theoretical basis and the common diagnostic methods for diagnostic purposes. He is able to understand the significance of the results of diagnostic laboratory investigations in the characterization of the major human diseases.

Course contents

- Laboratory test for the diagnosis of coagulation disorders. Laboratory tests for the evaluation of platelet function, coagulation cascade and fibrinolytic system; laboratory definition of the hypercoagulability disorders. Disseminated intravascular coagulation (DIC): pathophysiology of DIC; laboratory definition of the phases of coagulation cascade activation, fibrinolytic system activation and coagulation factor consumption.

- Laboratory tests for the diagnosis of hepatic disorders. Bilirubin and urobilinogen; serum enzymes indicative of cytolysis and cholestasis; albumin/globulin ratio; coagulation factors.

- Laboratory tests for the diagnosis of renal system disorders. Urine analysis (physical, chemical and microscopic examination); urea, creatinine and uric acid; clearance tests; functional tests.

- Serum proteins. Serum protein electrophoresis (SPE); SPE patterns associated to specific diseases; acute phase reactants (APRs) and erythrocyte sedimentation rate (ESR).

- Laboratory tests for the diagnosis of lipid disorders. Plasma lipoproteins and their metabolism; lipoproteins and atherosclerosis; quantitative and qualitative analysis of plasma lipoproteins.

- Laboratory tests for the diagnosis of diabetes. Classification of diabetes; metabolic effect of diabetes; laboratory tests for the diagnosis and for the follow-up of diabetic patients.

 

 

Readings/Bibliography

- Giorgio Federici: Medicina di Laboratorio. Terza edizione 2008, Mc Graw Hill libri Italia (Milano)

- Michael Laposata: Medicina di Laboratorio: la diagnosi di malattia nel laboratorio clinico. 2012, Piccin Nuova Libraria S.p.A. Padova.

- Italo Antonozzi e Elio Gulletta: Medicina di Laboratorio: Logica & Patologia Clinica. 2013, Piccin Nuova Libraria S.p.A. Padova.


 

Teaching methods

teaching lessons

Assessment methods

joint final oral examination. During the verification, at least two topics will be examined.

Teaching tools

Students receive the files of the presentations shown during the teaching lessons

Office hours

See the website of Lorenzo Montanaro