37185 - Histology and Embryology 1 (AK-B)

Course Unit Page

Academic Year 2018/2019

Course contents

General characteristics of the cell

Prokaryotes and eukaryotes General organization of the cell. Syncytia and plasmodia.

Cell membrane

Membrane structure and functions Fluid mosaic. Transport across cell membranes. Glycocalyx. Non-junctional adhesiveness. Permeability. Specializations.

Cytoskeleton

Microfilaments. Intermediate filaments. Microtubules. Composition and function of microfilaments. Amoeboid movement. Actin and ancillary proteins. Contractility of the cell. - Composition and function of the intermediate filaments. - Microtubules: tubulin, ancillary proteins and microtubule-organizing centers. Cilia and flagella

Intercellular junctions.

Cytoplasm

Cytosol and inclusions Chemical composition, physical properties, and functions of the cytosol.

Cytoplasmic organelles

Endoplasmic reticulum Structure and functions of rough and smooth reticulum.

Apparatus of Golgi Structure and functions. Vesicular transport. Exocytosis.

Lysosomes Structure and functions. Endocytosis. Clathrin-mediated endocytosis. Phagocytosis. Autophagocytosis.

Peroxisomes structure and function.

Mitochondria Size, shape, and structural organization of mitochondria. Functions and origin of the mitochondria. Mitochondrial DNA.

Nucleus Number, size and localization of the interkinetic nucleus. The nucleolus end the biogenesis of ribosomes.

Readings/Bibliography

Adamo et al. "Istologia di V. Monesi" editor Piccin VII edition

Adamo et al. "Istologia di V. Monesi" editor Piccin VI edition+ Cooper e Hausman "Fondamenti di Citologia" editor Piccin

Ginelli E, Malcovati M et al. "Molecole, Cellule e Organismieditor EdiSES

Zaccheo and Pestarino "Citologia, Istologia e Anatomia Microscopica" editor Pearson

Bacci et al. "BIOLOGIA: Cellula e Tessuti" editor EdiErmes

Teaching methods

Frontal lessons

Assessment methods

The learning assessment will include the examination of slides at light microscopy that is introductory to the oral exam. The students who failed the slide test are not admitted to the oral exam. The oral exam is a conversation about Cytology, Histology and Embryology according to the contents published in Histology and Embryology 1 and Histology and Embryology 2 courses. A low mark in one of the three parts precludes the whole exam. The student can choose to keep the mark of examination of slides (valid until December 2019) or to repeat it. In the opinion of the examiners, the final assessment will be the weighted average of the three results.

The online registration to the examination is mandatory.

Teaching tools

PowerPoint presentations.

The material used during the lessons is available since the first lesson by login at the Platform for teaching support service - Insegnamenti on line.

Office hours

See the website of Marcella Martinelli