07732 - Clinical Pathology

Course Unit Page

Academic Year 2018/2019

Learning outcomes

To allow the students to acquire the fundamental notions for a critical evaluation and interpretation of the results of the main clinical laboratory tests

Course contents

- The blood composition. Plasma, serum and corpuscular component; complete blood count (CBC); morphological features of the various blood corpuscular components. ABO blood group system, Rh blood group system.

- Laboratory tests for the diagnosis of anemia. Diagnosis and classification of anemia; microcytic anemia (iron deficiency and thalassemia); normocytic anemia (decreased red blood cell production, acute blood loss, hemolytic disorders), megaloblastic anemia (vitamin B12 or folic acid deficiency).

- Laboratory tests for the diagnosis of coagulation disorders. The principal phases of the hemostatic process; laboratory tests for the evaluation of platelet function and coagulation cascade

- Laboratory tests for the diagnosis of lipid disorders. Plasma lipoproteins and their metabolism; lipoproteins and atherosclerosis; quantitative and qualitative analysis of plasma lipoproteins.

- Laboratory tests for the diagnosis of diabetes. Classification of diabetes; metabolic effect of diabetes; laboratory tests for the diagnosis and for the follow-up of diabetic patients.

- Laboratory tests for the diagnosis of hepatic disorders. Bilirubin and urobilinogen; serum enzymes indicative of cytolysis and cholestasis; albumin/globulin ratio; coagulation factors.

- Laboratory tests for the diagnosis of renal system disorders. Urine analysis (physical, chemical and microscopic examination); urea, creatinine and uric acid; clearance tests; functional tests.

Readings/Bibliography

- Giorgio Federici: Medicina di Laboratorio. Terza edizione 2008, Mc Graw Hill libri Italia (Milano)

- Michael Laposata: Medicina di Laboratorio: la diagnosi di malattia nel laboratorio clinico. 2012, Piccin Nuova Libraria S.p.A. Padova.

- Italo Antonozzi e Elio Gulletta: Medicina di Laboratorio: Logica & Patologia Clinica. 2013, Piccin Nuova Libraria S.p.A. Padova.

Teaching methods

Frontal lessons for 24 hours (2 CFU)

Assessment methods

The final examination aims to assess that the student has acquired the fundamental notions for a critical evaluation and interpretation of the results of the main clinical laboratory tests which characterize the following pathological conditions: anemia; coagulation disorders; lipid disorders; diabetes; hepatic disorders, renal disorders.

 

Teaching tools

The slides shown during the lessons are available at the Web site: http://campus.unibo.it/ Username e password are reserved to students of Bologna University.

Office hours

See the website of Davide Trerè