13880 - Pharmacology and Pharmacotherapy

Course Unit Page

Academic Year 2018/2019

Learning outcomes

At the end of the course the student – will acquire basic knowledge, both educational and scientific grounds on natural, synthetic and biotechnological drugs; - will know the classes of drugs both in experimental preclinical level (pharmacokinetics, pharmacodynamics, side effects), both in their use in human pathology; - will acquire knowledge about the dosages and the main therapeutic strategies, as well as the association between drugs; - will know the therapeutic contraindications for the correct choice of the drug; - will be able to assess the risk-benefit and cost-effectiveness of a therapy

Course contents

Course contents:

I part:

Periferic nervous system and neuromuscolar junction
Cholinergic agonists and antagonists and cholinesterase inhibitory drugs
Adrenergic agonists and antagonists
Pharmacology of neuromuscolar transmission
Local anesthetics
Central nervous system

Antiepilectics
Drugs for Parkinson desease
Drugs used in the treatment of psychoses
Antidepressants
Opiates: agonists and antagonists
Ansiolitis

Treatment of central nervous system degenerative disorders
Drug of abuse  Cardiovascular and renal system
Drugs for the treatment of cardiac insufficiency and della ischemia myocardial
Antiarrhythmic drugs antiangina
Renin and angiotensin
Antihypertensive agents and the drug therapy of hypertension
Diuretics Immune system and inflammation
Non steroidal Antiinflammatory drugs
Glucocorticoids
Drugs acting on the blood
Hematopoietic agents Anticoagulant – Thrombolytic – Antiplatelet – Antifribinolytic drugs 

Bronchodilatators and other agents used in the treatment of asthma
Antitussive agents and mucolitics

Drugs affecting gastrointestinal function

Agents used for control of gastric acidity and peptic ulcers

Endocrinal  pharmacology: hormones and hormone antagonists
Hypothalamic and pituitary hormones
Estrogens, progestins, androgens and their antagonists
oral hypoglycemic agents
Thyroid and antithyroid drugs

II Part

Chemotherapy of protozoal infections

Antiprotozoal drugs (malaria)

Chemiotherapy of bacterial infections

Antibacterial drugs

Sulfonamides, trimethoprim-sulfamethoxazolo

Quinolones and urinary tract infections drugs

Penicillin, cephalosporin and other beta-lactam antibiotics

Aminiglycosedes

Tetracyclines, chloramphenicol, erithromycin and macrolids

Drugs used to treat tubercolosis

Anifungal drugs

Antiviral drugs

Cancer chemiotherapy   Antineoplastic drugs

Readings/Bibliography

S. GOVONI,  FARMACOLOGIA  con sito web,  Casa Ed. Ambrosiana I ed. italiana, Milano, 2014

B.G . KATZUNG, Farmacologia Generale e Clinica , Piccin . IX Edizione italiana sulla XII in lingua inglese, Piccin , 2014.

Goodman and Gilman " La basi farmacologiche della Terapia " XII ed . it . Zanichelli  2014.

RANG , DALE, RITTER, Farmacologia , VII Edizione, Elsevier , 2012.

 

Teaching methods

frontal lessons

Assessment methods

The final test consists of an oral examination. The examination verifies the achievements of the teaching goals: the knowledge of the basic principle of Pharmacology (pharmacotherapy). The final score leading to 8CFU will come out by means of 4 questions exam dealing with  topic related to the program.

The exam is integrated by a facultative written test dealing with one section of the program: Chemotherapy Module II). Once the student passes the written test he may decide to avoid the question on chemotherapy at the oral examination or do it if he wants to improve the score. Alternatively the students can directly present to the oral examination and receining 4 questuions, including Chemotherapy. The eritten test is made one per year and it is valid for one year.

Questions are presented concening Chemotherapy, Pharmacology of SNC, cardiovascular, respiratory, blood and endocrine section.

Further questions may be given in needed case. The test lastes about 30 minutes.

The final score will be the mean of the separate score obtained in the exam taking into account talso the written part, based on the capacity of the student to talk about the items and to demonstrate the knowledge of the pharmacological principles, together with the possibility to be rewarded with excellence scores when he is able to show a profound knowledge and specific property of language.

application to Almaesami

Teaching tools

power point presentations

Office hours

See the website of Patrizia Romualdi