Abstract
The development of age-appropriate and personalized medicines is still a necessity. For pediatric use, formulations must be tailored to accommodate child-specific characteristics such as age, weight, and swallowing ability. Moreover, specifically to antibiotic therapy, relevant limitations can be mentioned such as drug inappropriate biopharmaceutical properties, low stability in the gastrointestinal tract and bitter taste. The project p3Diatrics explored and combined innovative strategies with the final aim of obtaining suitable oral antibiotic formulations, specifically designed for various pediatric age groups. Formulations were manufactured using different 3D printing methodologies and characterized as regard the physico-chemical, technological, and functional properties. By combining both materials science and formulation technology fields, p3diatrics could impact current clinical scenarios, providing personalized dosage forms able to improve patient adherence to the therapy.
Dettagli del progetto
Responsabile scientifico: Angela Abruzzo
Strutture Unibo coinvolte:
Dipartimento di Farmacia e Biotecnologie
Coordinatore:
Università degli Studi di URBINO "Carlo Bo"(Italy)
Contributo totale Unibo: Euro (EUR) 57.786,00
Durata del progetto in mesi: 24
Data di inizio
16/10/2023
Data di fine:
15/10/2025
