Artificial Intelligence to investigate the mutual interplay of Metabolome and Transcriptome in Gastric Cancer heterogeneity

PRIN 2022 Giorgi

Abstract

Description: The project aims at identifying cancer-related mRNAs and metabolites, and to develop a machine learning algorithm to be able to predict metabolites based on gene expression profiles. The project will implement state-of-the-art transcriptomics, metabolomics and bioinformatics tools in gastric and other cancers, in order to understand whether the heterogeneity observed in patients has molecular basis. Goals: to better understand the interplay between metabolome and transcriptome. Expected results: at least one peer-reviewed publication in international journals, describing the role of gene expression and/or metabolite abundance in cancer.

Dettagli del progetto

Responsabile scientifico: Federico Manuel Giorgi

Strutture Unibo coinvolte:
Dipartimento di Farmacia e Biotecnologie

Coordinatore:
ALMA MATER STUDIORUM - Università di Bologna(Italy)

Contributo totale di progetto: Euro (EUR) 196.825,00
Contributo totale Unibo: Euro (EUR) 11.089,00
Durata del progetto in mesi: 24
Data di inizio 28/09/2023
Data di fine: 28/02/2026

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