79091 - ORGANIC CHEMISTRY FOR NANOTECHNOLOGIES WITH LABORATORY

Conoscenze e abilità da conseguire

Organic chemistry for nanotechnology represents the next generation of innovation beyond the current applications of organic chemistry. Preliminarily, basic principle of nanotechnology will be introduced and a quick overview of the metallic nanoparticles’ synthetic methods will be presented to the student. Main objective of the course is the understanding the role of the organic functional groups in the Self Assembled Monolayers (SAMs) of several metallic nanoparticles. At the end of the course the student will face the application of the organic chemistry for nanotechnologies to the Nanomedicine with some experimental laboratories. The use of the instruments DLS (Dynamic light scattering) will be also part of the skills (size determination of the nanoparticles and more information) that will be accomplished at the end of the course.

Contenuti

Prerequisites:

Fundamentals on transition metal's features. Fundamentals of basic organic chemistry functional groups together with structural recognition. Fundamentals of polymer chemistry as Molecular weight determination and the basic rheological properties

Contents:

1. Introduction to the organic chemistry for nanoscience

2. Silica Nanoparticles

3. Gold Nanoparticles

4. Quantum-Dots

5. Iron-oxide Nanoparticles

6. Carbon Nanoparticles

7. Soft Organic Nanoaprticles: Dendrimers

8. 7. Soft Organic Nanoaprticles:Carbohydrates

9. Soft Organic Nanoaprticles:Proteins

10. Preparation, Purfication and Conjugation techniques

11. Nanomedicine applications

 

Testi/Bibliografia

Soft nanoparticles for biomedical applications. Royal Society of Chemistry. J. Callejas-Fernandez, J. Estelrich, M. Quesada-Perez, J. Forcada. 2014.

 

Several papers published in the literature

Metodi didattici

Theoretic lessons will be combined with the analysis of modern and advanced literatures to apply the concepts explained.

Two laboratories will be dedicated to the synthesis and spectroscopic characterization of organic soft nanoparticles

Modalità di verifica e valutazione dell'apprendimento

The final examination will determine the level reached by the student in the objectives set out in the " Learning outcomes”

The assessment of the learning consists in oral presentation of the students on selected research topics learned during the course.

To carry out the oral exam registration is required through "Alma exams ", in respect of the mandatory deadlines.

The students will have to use the power point with a maximum of 15 slides according to materials deduced using 2-3 papers.

Mark will consider how the student will sketch out the "state of the art", 15 points, and how he/she will describe the results obtained in the selected papers, 15 points.

Attendance the laboratories will give 3points each.

The maximum score is therefore 36 out of 30, the honor (cum laude) is automatic after reaching 33 points.

Strumenti a supporto della didattica

Presentations in PDF file by the teacher, protected under password, are available on-line in the specific list of distribution on ALMA Campus

Orario di ricevimento

Consulta il sito web di Mauro Comes Franchini