90932 - BIOMOLECULAR BASIS OF ANATOMICAL PATHOLOGY

Conoscenze e abilità da conseguire

Discuss the principal epidemiologic, morphologic, phenotypic, clinicopathologic features, and etiopathogenesis of common neoplastic and non neoplastic disorders, focusing on cardiovascular and neuromuscolar disorders. Describe the methods used to process and analyze tissue samples for diagnostic Anatomic Pathology, including histopathology and ultrastructural laboratory instrumentation and devices. Discuss innovative technologies for early diagnosis of disease, and for the identification of new molecular targets for tumor therapies.

Contenuti

definition of Pathological Anatomy

Methods and Techniques in Pathological Anatomy

Tumor classification

malignant Tumor of Thyroid

SNC tumor classification

Molecular aspects of SNC Tumor

Pathogenetic mechanism of ischemic myocardium disease

Neuromuscular disease: muscle pathology

Methods and techniques in muscle pathology diagnostics

Elementary lesions of glomerular diseases

Electron microscopy : Transmission and scanning electron microscopes

Protocols in sample preparation for ultrastructural diagnosis

Ultrastructural markers in Tumor diagnosis

Case study

Student working groups about main diagnostic issues

The Course is completed by 1 CFU of practical activity in the Laboratory at Laboratorio di Morfologia (FABIT). Specific muscle disease cases will be directly studied and analyzed at light microscopy (30 microscopes are available) and discussed in student group and in a plenary session guided by both the teacher and tutor

Testi/Bibliografia

Kumar, Cotran, Robbins "Basic Pathology", Saunders eds

Metodi didattici

conventional lectures and student workig group

case study

practical laboratory activity (Laboratorio di Morfologia, FABIT)

Modalità di verifica e valutazione dell'apprendimento

the student will be evaluated after oral examination about:

1. general aspect of pathological Anatomy (techniques and methodology)
2. specific pathology (morphological, Ultrastructural and molecular aspect of main human diseases)
3. Discussion on ultrastructural micrograph.

Final vote is the media value obtained by each question (1, 2 and 3) vote

Strumenti a supporto della didattica

Ex -cathedra teaching, conventional

Student working Group about main diagnostic issues

Case study and plenary discussion

Orario di ricevimento

Consulta il sito web di Giovanna Cenacchi