46248 - General Pharmacology

Academic Year 2017/2018

  • Teaching Mode: Traditional lectures
  • Campus: Bologna
  • Corso: First cycle degree programme (L) in Nursing (cod. 8473)

Learning outcomes

Learning outcomes will be: a)  basic knowledge about drug metabolism (administration, clearance, therapeutics, adverse effects)

Course contents

GENERAL PHARMACOLOGY. General pharmacokinetics: movement of drugs across cell membranes;  routes of administration and absorption; bioavailability;  distribution of drugs in the body; volume of distribution, binding to plasma proteins; drug metabolism; excretion; time-course of drug plasmatic contents (after single or repeated administration). General pharmacodynamics: targets and mechanisms of drug  action; dose-response curve; agonists, partial agonists, antagonists; individual variations (effects of age, pathological states, drug interactions, tolerance, placebo effects). General toxicity: side-effects, overdose, idiosyncratic and allergic reactions; teratogenesis and foetal toxicity; carcinogenesis; drug dependency. Clinical evaluation.

Readings/Bibliography

Michelle A. Clark, Richard Finkel, Jose A. Rey, Karen Whalen “Pharmacology” Lippincott Williams and Wilkins

Teaching methods

Plenary lecture

Assessment methods

Written examination

Teaching tools

Power Point presentation (the material could be downloaded at amsacta.unibo.it )

Office hours

See the website of Roberto Rimondini Giorgini