- Docente: Massimiliano Bonafè
- Credits: 8
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: Single cycle degree programme (LMCU) in Medicine and Surgery (cod. 8415)
Learning outcomes
The students will learn the etiology of the disease processes, the pathogenetic mechanism of their development, the basic reactions to abnormal stimuli and the morphological changes they induce in cells and tissues, together with the systemic and functional consequences for the organism. By the elaboration of molecular, morphologic, microbiologic and immunologic knowledges, the students will understand the wherefores of the signs and symptoms manifested by patients and will be provided with a sound foundation for evidence based medicine.
Course contents
COURSE CONTENTS
ENVIRONMENTAL PATHOLOGY Physical injuries, Local and systemic effects of high and low temperatures, Smoke damage Chemical injuries; Ethanol: absorption and detoxification, acute and chronic toxic effects; Local and systemic effects of endotoxins, Pathogenic action of exotoxins (diphtheria, cholera, tetanus and botulinum)
CELLULAR PATHOLOGY Cell adaptations, Atrophy Hypertrophy , Hyperplasia, Metaplasia and dysplasia, Cell jnjury, Etiopathogenesis of cellular damage, Vacuolar degeneration; Steatosis: etiology and classification,pathogenic mechanisms, Cell death, Apoptosis, Necrosis, pathologic calcifications, amyloidosis
RESPONSE TO THE DAMAGE Acute inflammation, General characteristics, Etiology, Vascular phenomena, Exudative oedema, Cell phenomena, Phagocytosis, Chemical mediators: plasma proteases, Chemical mediators: cellular products, Classification of acute inflammations, Outcomes and systemic effects; Chronic inflammation, Granulomatous forms, Pneumoconiosis, Etiopathogenesis of the tuberculousosis, Granulation tissue, Wound healing, sclerosis, cirrhosis
PATHOPHYSIOLOGY haemostasis, haemorragic diseases and thrombosis; Etiopathogenesis of shock, hypertension, infarction, hypoxia and cyanosis Classification of arteriosclerosisPathogenesis of atheroma; Consequences of atherosclerosis; pathogenesis of infarction, hypoxia, cyanosis; pathogenesis of infarction; Etiopathogenesis of fever, oedema, diabetes mellitus
Readings/Bibliography
V. Kumar, A.K. Abbas, J.C. Aster. “Robbins & Cotran - Pathologic Basis of Disease, 9thedition, 2015, Elsevier Ed
Teaching methods
teacher led lectures
Assessment methods
viva test; two questions
one to ascertain theoretical knowledge
one entails the assessment of the skills acquired at the Laboratory of Histopathology
Online registration via AlmaEsami is mandatory.
Teaching tools
lectures slides hosted at AMS campus web site
Office hours
See the website of Massimiliano Bonafè