Modulators of intracellular chloride concentration

The present invention relates to a compound of Formula I, a pharmaceutical composition comprising the same and their use in the treatment or prevention of pathological conditions associated to depolarizing GABAergic transmission including, for example, Down syndrome and autism

Patent title Modulators of intracellular chloride concentration
Thematic area Health
Ownership ISTITUTO ITALIANO DI TECNOLOGIA - sede di Genova, UNIVERSITA' DEGLI STUDI DI GENOVA, FONDAZIONE TELETHON, ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA
Inventors Marco Borgogno, ANNALISA SAVARDI, LAURA CANCEDDA, ANDREA CONTESTABILE, MARCO DE VIVO
Protection International (PCT)
Licensing status not availablefor license agreement
Filed on 02 April 2019

Page published on: 06 May 2019