87822 - Industrial Analytical Chemistry with Laboratory M

Course Unit Page

SDGs

This teaching activity contributes to the achievement of the Sustainable Development Goals of the UN 2030 Agenda.

Quality education Sustainable cities Climate Action

Academic Year 2022/2023

Learning outcomes

The course is aimed to acquire the capability to use the suitable instrumentation, on the bases of the characteristics of the analyte, matrix and amount of sample. To project a scheme of an analytical procedure, starting from appropriate sampling plans, even with technical regulation. The students will be able to evaluate the quality of an analytical or industrial process with statistical tests and controls charts.

Course contents

Learning Objectives

Knowledge and Comprehension

At the end of the course, students will know:

  • statistical methods to evaluate results given by sundry operators
  • how to do the quality control of processes
  • easy procedure to design experiments
  • principle and instrumental assets of spectroscopic and electrochemical techniques, also hyphenated
  • principle and instrumental assets of surface analysis
  • ·operating principle of sensors and bio-sensors

At the end of the course, students will have understood:

  • the role of statistical procedure in the management and control of analytical and industrial processes
  • issues related to analyte detection in trace and ultra-trace analysis
  • relationships between energy levels of an analyte and the desiderated result
  • relationships between mass transfer and the electrochemical signal of an analyte

Ability and Competence

At the end of the course the student will be able to:

  • evaluation of the analytical result coming from two or more operators
  • build and use control curves for quality evaluation of analytical process
  • find possible strategies to optimize a chromatographic separations
  • use small and medium instrumentation (atomic absorption and emission, electrochemical stations)
  • detect correct procedures to control interferences and limit of detection
  • design an appropriate analytical procedure for two or more analytes determinations

Topic of the course

Sampling theory, control charts, analysis of variance (ANOVA). Accreditation and test labs. Basics of experimental design. Sampling in industrial field.

Elemental analysis.

Spectroscopy and spectrometry. Atomic spectrometry in absorption and emission mode. Graphitic furnace, plasma.

Analysis of surfaces by X-Ray methods. X-ray - matter interaction. Basic of x-ray absorption and emission spectroscopy. X-ray diffraction. Photoelectron spectroscopy. Industrial application of X-ray analysis.

Reflection and Refraction of light. Total internal reflection. Optical fibers. Attenuated total reflection (ATR). Near infrared spectroscopy: principles and industrial applications. Raman spectroscopy.

Hyphenated techniques. Detection in Mass Spectrometry. Basics of ICP-MS, GC-MS, SIMS.

Electroanalytical Chemistry and Sensors. Electron transfer. Mass transport (diffusion, convection, migration). Controlled potential techniques (cronoamperometry, cronocolumbometry,, cyclic voltammetry)

Techniques for the trace and ultratrace analysis (anodic, cathodic and potentiometric stripping)

Modified electrodes for sensors applications

Amperometric sensors and biosensors

Practical

The course is completed by some laboratory work (practical).

PRE-REQUIREMENTS OF KNOWLEDGE AND ABILITY TO FOLLOW THE COURSE

In general, the knowledge and skills acquired in the following courses are required: Mathematics, Physics, Analytical Instrumental Chemistry

In particular, students must:

  • be able to perform graphs and calibration curves
  • be able to prepare solutions at a given concentration (also low concentration) with the appropriate precision
  • Possess basic element of optics and algebra
  • be able to use simple analytical instruments

Readings/Bibliography

Highly recommended

  1. H.H. Willard, R.R. Merritt, J.A. Dean, F.A. Settle. Instrumental Methods of Analysis 7th edition. Wadsworth Publishing Company, 1988
  2. J.C. Miller and J.N. Miller, Statistics and Chemometrics for Analytical Chemistry, 6th ed., Prentice Hall (UK), 2010

Optional

  1. M.Castino, E. Roletto, Statistica applicata. Trattamento dei dati per studenti universitari, ricercatori e tecnici. Piccin, 1999 (ISBN: 9788829909353)
  2. D.A. Skoog, D.M. West, F.J. Holler, S.R. Crouch, F Chimica Analitica Strumentale, III Ed., Edises, 2009 (ISBN:9788879593427).
  3. K. A. Rubinson, J. F. Rubinson, Chimica Analitica Strumentale, Zanichelli, 2002
  4. P.M.S. Monk "Fundamentals of Electroanalytical Chemistry" J. Wiley & Sons, New York, 2002.

Teaching methods

The course involves front lectures and laboratory work.

As concerns the practical experiences of this course, all students must attend Module 1, 2 [https://www.unibo.it/en/services-and-opportunities/health-and-assistance/health-and-safety/online-course-on-health-and-safety-in-study-and-internship-areas] online, while Module 3 on health and safety is to be attended in class. Information about Module 3 attendance schedule is available on the website of the degree programme.

Assessment methods

The assessment of the learning consists in final written exam on some selected research topics learned during the course plus the laboratory assessment.

The written exam is made up of: a) multiple-choice questions and true/False questions; B) open answer questions; C) execution of problems and exercises related to the acquired knowledge and skills acquired on the theoretical, practical and applied contents of the course. The test may also include questions related to previous knowledge not explicitly covered by the course but resulting essential for the understanding of the course.

The duration of the written test is 2 hours, and using the eol.unibo.it platform

The use of textbooks and lessons slides is expressly forbidden. It is compulsory to have a pc, and any outils like pencils, rulers, team, rubber, pencil sharpeners.

It is possible to reject a positive grade only twice.

Teaching tools

Lecture slides and other material useful for exam preparation is made available to the student electronically via the Internet. To get the teaching material the student must be connected to the specific web site (iol.unibo.it).

Office hours

See the website of Marco Giorgetti

See the website of Barbara Ballarin

See the website of Andreas Stephan Lesch