39196 - Methodologies for Clinical Research (CE)

Course Unit Page


This teaching activity contributes to the achievement of the Sustainable Development Goals of the UN 2030 Agenda.

Good health and well-being

Academic Year 2019/2020

Learning outcomes

After completing this modulethe student will haveknowledgeofthe aims andmethodsofevidence-based practice, hewill havethe ability to applyknowledge and understandingin relationto the formulation ofclinical questions, conductingliterature searchesanddevelopingresearch protocolsin physiotherapy

Course contents

Search strategies of major databases




Cochrane Library

Guidelines and point of care

Primary studies

-Experimental Studies:

-Randomized Controlled Clinical Trial (RCT)

Observational Studies:

-Cohort (Incidence, Longitudinal Study) Study

-Case-Control Study

-Case Series

-Case Report

Secondary studies

-Systematic reviews



The paradigm"Evidence Based Practice"

E.B.P. definition, history, examplesof application
The four steps of EBP

1. Formulation of the clinical question (PICO)

2. Search for evidence in the literature

3. Critical evaluation of the evidence

4. The application of the results to the individual patient


Herbert R, Jamtvedt G, Hagen KB, Mead J. Fisioterapia basata sulle evidenze. 2005, EDRA LSWR, Milano.

Chiari P, Mosci D, Naldi E. L'infermieristica basata su prove di efficacia. Guida operativa per l'Evidence Based Nursing. 2006, McGraw-Hill Companies [http://www.deastore.com/editore/McGraw-Hill%20Companies.html] .

Attena F. Epidemiologia e valutazione degli interventi sanitari. 2004, Piccin, Padova.

Teaching methods

Short lectures
Individual exercises in the PC with Internet

Assessment methods

Written test and practical test

written test: questions with a short open answer

practical test: research in one of the main databases

Scoring for the written test = 0-22

Scoring for the practical test = 0-8

L.a.p. (Acceptable level of performance) = 18;

Teaching tools

PC and video projector
PC with internet connection

Links to further information


Office hours

See the website of Lucia Bertozzi