- Docente: Andrea Buscaroli
- Credits: 1
- SSD: MED/14
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Ravenna
- Corso: Single cycle degree programme (LMCU) in Medicine and Surgery (cod. 5708)
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from Apr 11, 2024 to Apr 22, 2024
Learning outcomes
The aim of the course is to provide the student with the theoretical and practical knowledge of the main acute and chronic nephropathies, primary and secondary to systemic diseases.
The course includes an initial part dedicated to an anatomical-pathological recall and to the clinical and instrumental approach of the diagnostic pathways, subsequently it examines the main nephropathies outlining their pathogenesis, the clinical picture and histopathological characterization. The diagnostic aspect is treated, including the possible differential diagnoses, and hints of therapy are introduced.
At the end of the course the student will have the knowledge relating to the pathways of acute kidney disease and acute kidney injury including the basics of conservative and replacement therapy.
Course contents
Recall of anatomy and physiology
Nephrological semeiotics (clinical, laboratory tests, imaging diagnostics, renal biopsy)
Water balance and pathological conditions, acid-base and electrolyte balance disorders
Glomerular nephropathies: clinical presentation and pathogenetic mechanisms with insights into nephritic and nephrotic syndromes
Minimal change GN, focal sclerosing GN, membranous GN
Post streptococcal/post infectious GN, IgA nephropathy, membranoproliferative GN, and complement-related glomerulopathies
Rapidly progressive GN and ANCA-related vasculitides
Secondary glomerular nephropathies: Lupus nephritis, Diabetic nephropathy, Glomerulopathies in the course of multiple myeloma and/or Amyloidosis, Glomerulopathies in the course of Cryoglobulinemia
Thrombotic microangiopathy and haemolytic uremic syndrome
Acute kidney injury (AKI), pathophysiology and main clinical pictures: pre-renal, organic and post-renal forms
Hereditary nephropathies: Adult polycystic disease and other cystic nephropathies, Alport syndrome, Fabry disease
Interstitial nephropathies: acute and chronic pyelonephritis, analgesic and immuno-allergic nephropathies
Kidney changes during pregnancy
Renovascular hypertension, renal infarction, atheroembolic nephropathy
Chronic kidney disease: epidemiology, and staging; progression of renal failure; main clinical alterations in the conservative phase and in the uremic phase including bone-mineral disease.
Conservative therapy including the nutritional aspect
Dialysis replacement therapy (hemodialysis and peritoneal dialysis)
Kidney transplant
Readings/Bibliography
Harrison, Principi di medicina interna, 20ª ed., Milano, CEA Casa Editrice Ambrosiana, 2021 (o 21a edizione in inglese)
Garibotto-Pontremoli, Manuale di Nefrologia, ed Minerva Medica
Per consultazione: Comprehensive Clinical Nephrology, R. J. Johnson; J. Feehally; J. Floege; M. Tonelli, Elsevier Ed.
Teaching methods
Lectures and interaction with students
Assessment methods
Three oral exam sessions
Teaching tools
Updated material (pdf format)
Office hours
See the website of Andrea Buscaroli