- Docente: Daria Vincenzi
- Credits: 3
- Language: Italian
- Moduli: Daria Vincenzi (Modulo 1) Alessandra Stancari (Modulo 2)
- Teaching Mode: In-person learning (entirely or partially) (Modulo 1); In-person learning (entirely or partially) (Modulo 2)
- Campus: Bologna
- Corso: First cycle degree programme (L) in Biomedical Laboratory techniques (cod. 8484)
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from Oct 28, 2026 to Dec 16, 2026
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from Jan 12, 2027 to Jan 28, 2027
Learning outcomes
At the end of the course, students will have acquired the knowledge and skills related to the analytical processes covered by this seminar.
Course contents
Preparatory course for the practical internship, consisting of two modules (36 hours in total) delivered through lectures.
MODULE 1: Fundamentals of Analytical Chemistry (24 hours – 2 ECTS)
a) Analytical Chemistry in the biomedical laboratory
- Introduction to Analytical Chemistry.
- The analytical process: pre-analytical, analytical and post-analytical phases.
- The role of Analytical Chemistry in laboratory diagnostics.
b) Analytical measurement
- Qualitative and quantitative analysis.
- Accuracy, precision, sensitivity, specificity and measurement errors.
- Principles of quality control and validation of analytical methods.
c) Main analytical techniques used in biomedical laboratories and their principles
- Optical techniques: spectrophotometry.
- Separation techniques: high-performance liquid chromatography, gas chromatography and electrophoresis.
- Electrochemical techniques: potentiometry.
- Immunochemical techniques (antigen-antibody reactions): ELISA, CLIA and FEIA.
- Mass spectrometry-based techniques: mass spectrometry and tandem mass spectrometry.
d) Analytical data
- Interpretation of analytical results.
- Principles for interpreting the main instrumental outputs.
MODULE 2: Pharmaceutical Production Techniques (12 hours – 1 ECTS)
- Introduction to the activities of the Hospital Pharmacy.
- Pharmaceutical production and Good Preparation Practices for medicinal products.
- Sterile and non-sterile galenic production.
- Principles of artificial nutrition: parenteral nutrition mixtures, clinical and pharmaceutical aspects, and formulation of parenteral nutrition mixtures.
- Pharmacology of antineoplastic agents and therapeutic regimens.
- Computer-assisted preparation and aseptic, safe handling of antineoplastic therapies.
- Clinical trials and the production of investigational medicinal products.
- Laboratory visit.
Readings/Bibliography
MODULE 1 – Fundamentals of Analytical Chemistry
- D'Ovidio C., De Grazia U., Lanuti P. Chimica Analitica Clinica. EdiSES, Naples.
- Cozzi R., Protti P., Ruaro T. Elementi di chimica analitica strumentale. Tecniche di analisi per biotecnologie ambientali e sanitarie. 3rd ed. Zanichelli, Bologna.
- Lecture slides.
MODULE 2 – Pharmaceutical Production Techniques Italian
- Official Pharmacopoeia, 12th edition.
- Good Preparation Practices for Medicinal Products.
- SINPE Guidelines for Parenteral and Enteral Nutrition.
- Lecture slides.
Teaching methods
Lectures.
Theoretical and practical exercises.
The Wooclap platform will be used for formative assessments to monitor students' level of understanding throughout the course.
Assessment methods
MODULE 1
Multiple-choice test and open-ended questions. In the event of failure to pass the written assessment or inability to attend the examination session, the examination will consist of an oral examination.
MODULE 2
Multiple-choice test.
Teaching tools
Teaching materials provided in .pptx and .pdf formats.
Use of the Virtuale and Wooclap platforms.
Office hours
See the website of Daria Vincenzi
See the website of Alessandra Stancari