- Docente: Maria Giulia Bacalini
- Credits: 1
- SSD: BIOS-09/A
- Language: Italian
- Teaching Mode: In-person learning (entirely or partially)
- Campus: Rimini
- Corso: First cycle degree programme (L) in Nursing (cod. 8475)
Learning outcomes
The student, at the end of the module, thanks to the knowledge of the fundamental principles of chemistry and organic molecules of biological interest, is able to evaluate biological and biochemical parameters in biological samples and in vivo, also in relation to pathophysiological states, at different levels of structural organization, from single molecules to cells, tissues, organs, up to the whole organism.
Course contents
- Biomarkers: definition and types; development and validation of biomarkers; performance of a test.
- Precision medicine: definitions; role of biomarkers in precision medicine; molecular diagnostics techniques and their applications; next-generation sequencing.
- Epigenetics: principles; epigenetic biomarkers.
- Liquid biopsy: biomarkers based on circulating nucleic acids.
- Biomarkers in drug development: umbrella and basket clinical trials
- Protein-based biomarkers (overview)
Readings/Bibliography
- Teaching materials in pdf
- M. Ciaccio e G. Lippi, Biochimica Clinica e Medicina di Laboratorio, EDISES
Teaching methods
Lectures with powerpoint presentations
Assessment methods
Learning is assessed solely through a final examination, which verifies the acquisition of the expected knowledge and skills.
The exam is unified for the Integrated Course in Pathological Sciences and is conducted in written form, using a computer in a computer lab.
The written test will be taken in the following format:
A single test of 60 questions covering all subjects: General Pathology (30), General Pharmacology (10), Clinical Pathology (10), Clinical Biochemistry(10).
Duration: 50 minutes.
Minimum passing score: 36 correct answers out of 60.
Students with learning disorders and\or temporary or permanent disabilities: please, contact the office responsible (https://site.unibo.it/studenti-con-disabilita-e-dsa/en/for-students ) as soon as possible so that they can propose acceptable adjustments. The request for adaptation must be submitted in advance (15 days before the exam date) to the lecturer, who will assess the appropriateness of the adjustments, taking into account the teaching objectives.
Teaching tools
Power point presentations, video
Office hours
See the website of Maria Giulia Bacalini