75267 - General Pathology

Learning outcomes

At the end of the module the student has the knowledge and the ability to understand the main causes of disease, the manifestations and the main biological mechanisms of degenerative and regenerative tissue processes. The student knows and has the ability to understand the pathogenetic processes and the fundamental clinical signs related to the main acute and chronic inflammatory diseases.

Course contents

-Concept of disease, etiology and pathogenesis

Cellular adaptations
- Atrophy
- Hypertrophy
- Hyperplasia
- Metaplasia, dysplasia and neoplasia

Cell jnjury
- Etiopathogenesis of cellular damage

Cell Death
- Apoptosis
- Autophagy
- Necrosis

Basic concepts of immunology
- Innate immunity
- Adaptive immunity
- Immunopathology

Acute inflammation
- General characteristics
- Etiology
- Vascular phenomena
- Exudative oedema
- Cell phenomena
- Phagocytosis
- Chemical mediators
- Classification of acute inflammations
- Outcomes and systemic effects

Cronic inflammation
- Chronicization of acute forms
- Granulomatous forms

Tissue repair

Pathophysiology of vessels and circulation
- Classification of arteriosclerosis
- Etiopathogenesis and consequences of atherosclerosis
- Etiopathogenesis and consequences of thrombosis
- Etiopathogenesis and consequences of embolism
- Etiopathogenesis of the infarction
- Etiopathogenesis of localized and generalized transudative edema

 

 

Readings/Bibliography

V. Kumar, A.K. Abbas, J.C. Aster, A.T. Deyrup “Robbins - Elementi di patologia e fisiopatologia”, 2024, Casa Editrice Edra, Milano

G.M. Pontieri - “Elementi di Patologia generale e Fisiopatologia generale”. IV edizione, Piccin Editore

Teaching methods

The course consists of 24 hours of lectures.

Assessment methods

The final examination aims to assess the achievment of the objectives of the integrated course.

The final grade (maximum 30 points) is the result of the synthesis of final evaluation of different subjects belonging to the integrated course. It is the CFU-weighted average of grades obtained in specific questions of the different subjects.

Examination is passed if the grade in each subjects is not lower than 18 points.

General Patology examination:

written exam consisting of multiple choice and open questions, aimed at ascertaining the student's knowledge of the topics in the program. The exam of the module is considered passed with at least 18 points.

Students have 45 minutes to complete the written exam.
The use of supporting materials such as textbooks, notes, or computer media is not permitted during the exam.

Students with special needs (BES) are asked to contact the office in charge and follow the usual procedures for agreeing on how to conduct the exam (need to additional time and/or choice of oral exam, use of maps, use of pc, etc.).

Teaching tools

Students can access online to the teaching material made available by the teacher at http://virtuale.unibo.it

 

Office hours

See the website of Letizia Polito