- Docente: Paolo Di Bartolo
- Credits: 1
- SSD: MED/13
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Ravenna
- Corso: Single cycle degree programme (LMCU) in Medicine and Surgery (cod. 5708)
-
from Oct 17, 2024 to Dec 05, 2024
Learning outcomes
Sex and gender are important health determinants and,
as such, they should be taken into account in the planning
of personalized medicine approaches. The term sex should properly refer to individual biological characteristics mainly linked to genetic background and sexual hormones, while gender implies a multidi-
mensional concept, influenced by social, religious, and cultural determinants, as well as by individual behavior.
However, such aspects usually interact and their specific contribution to the incidence and prevalence of several non-transmissible chronic diseases, like cardiovascular diseases (CVD), neurodegenerative diseases, cancer, obesity, and diabetes, remains undefined.
The purpose of our meetings will be to better understand the complex relationship linking sex/gender and long-term complications of type 1 (T1DM) and type 2 diabetes (T2DM).
Course contents
Diabetes Definition, Incidence and prevalence and burden of Disease by sex and gender
Factors contributing to Sex and Gender differences in T2DM (Biological Factors- Non biological Factors - Comorbidities)
Sex- and gender-differences in macrovascular complications of T2DM and T1DM
Sex and gender differences in microvascular complications and NAFLD inT2DM and T1DM (Retinopathy, . Neuropathy, Diabetic Foot Syndrome)
Sex- and gender-differences in chronic long-term complications of
type 1 and type 2 diabetes mellitus in Italy
Implications for clinical practice and future perspectives in care of Diabetes
Readings/Bibliography
Russo GT, Manicardi V, Rossi MC, Orsi E, Solini A. Sex- and gender-differences in chronic long-term complications of type 1 and type 2 diabetes mellitus in Italy. Nutr Metab Cardiovasc Dis. 2022 Oct;32(10):2297-2309. doi: 10.1016/j.numecd.2022.08.011. Epub 2022 Aug 18. PMID: 36064685.
Huebschmann AG, Huxley RR, Kohrt WM, Zeitler P, Regensteiner JG, Reusch JEB. Sex differences in the burden of type 2 diabetes and cardiovascular risk across the life course. Diabetologia. 2019 Oct;62(10):1761-1772. doi: 10.1007/s00125-019-4939-5. Epub 2019 Aug 27. PMID: 31451872; PMCID: PMC7008947.
Johnson ML, Preston JD, Rashid CS, Pearson KJ, Ham JN. Sex differences in type 2 diabetes: an opportunity for personalized medicine. Biol Sex Differ. 2023 Dec 13;14(1):88. doi: 10.1186/s13293-023-00571-2. PMID: 38093356; PMCID: PMC10716945.
Giandalia A, Russo GT, Ruggeri P, Giancaterini A, Brun E, Cristofaro M, Bogazzi A, Rossi MC, Lucisano G, Rocca A, Manicardi V, Bartolo PD, Cianni GD, Giuliani C, Napoli A. The Burden of Obesity in Type 1 Diabetic Subjects: A Sex-specific Analysis From the AMD Annals Initiative. J Clin Endocrinol Metab. 2023 Oct 18;108(11):e1224-e1235. doi: 10.1210/clinem/dgad302. PMID: 37247381; PMCID: PMC10584007.
American Diabetes Association Professional Practice Committee. Standards of Care in Diabetes-2024. Diabetes Care. 2024 Jan 1;47(Supplement_1):S1-S4. doi: 10.2337/dc24-SINT. PMID: 38078587; PMCID: PMC10725799.
Russo G, De Cosmo S, Di Bartolo P, Lucisano G, Manicardi V, Nicolucci A, Rocca A, Rossi MC, Di Cianni G, Candido R; AMD Annals Study Group. The quality of care in type 1 and type 2 diabetes - A 2023 update of the AMD Annals initiative. Diabetes Res Clin Pract. 2024 Jul;213:111743. doi: 10.1016/j.diabres.2024.111743. Epub 2024 Jun 13. PMID: 38878867.
Teaching methods
Lectures supported by use of slides
Assessment methods
multiple choice quizzes
Teaching tools
Slides and original papers
Office hours
See the website of Paolo Di Bartolo