00768 - General Pathology

Academic Year 2015/2016

  • Teaching Mode: In-person learning (entirely or partially)
  • Campus: Bologna
  • Corso: First cycle degree programme (L) in Orthopaedics techniques (cod. 8483)

Learning outcomes

At the end of the course the student knows the concept of disease, the bases of etiology and pathogenesis, the reversible and irreversible cell damage. The student knows the molecular and cellular bases of the acute and chronic inflammatory responses, of the reparative process and of the normal and pathological immune response; the student knows the etiopathogenesis of diseases of interest to the professional Orthopaedic Technician.

Course contents

Programme / Content

- Definition and object of General Pathology. Concept of disease. Etiology and pathogenesis

- Cell adaptations: atrophy, hypertrophy, hyperplasia, metaplasia

- Reversible and irreversible cell damage

- Necrosis and apoptosis

- Normal immune response (cells and molecules of the immune system, humoral and cellular defense against infectious diseases) and pathological immune response (damage by hypersensitivities: Type I, anaphylactic; Type II, cytotoxic; Type III, by immune complex; Type IV, cell-mediated. Autoimmune diseases)

- General Pathology of microbial infections with particular reference to post-surgical orthopedic infection

- Acute inflammation. Etiology and signs, pathogenesis, cells and chemical mediators, vascular phenomena and formation of exudate, cellular phenomena, chemotaxis and phagocytosis, fever and other systemic effects

- Chronic Inflammation

- Reparative process

- An outline of:

• Atherosclerosis and Arteriosclerosis

• Thrombosis and Haemostasis

• Diabetic Foot

• Anemia and Thalassemia

Readings/Bibliography

- Pontieri, Elementi di Patologia Generale per i Corsi di Laurea in Professioni Sanitarie, 3a edizione, Piccin

- Poli-Columbano, Compendio di Patologia Generale e Fisiopatologia, Edizioni Minerva Medica

Teaching methods

Lectures and laboratory demonstrations

Assessment methods

Written examination on open questions

Teaching tools

Projecting slides and photomicrographs. The teaching materials will be provided directly by the Teacher, on CD-ROM, after the end of the lessons course. Alternatively, the teaching material of the lectures will be made available in AMS Campus-Alma DL and password for access to the files will be provided directly by the Teacher during lessons.

Office hours

See the website of Carla Renata Arciola