66690 - Enzyme Sructure Catalysis

Academic Year 2014/2015

  • Teaching Mode: In-person learning (entirely or partially)
  • Campus: Bologna
  • Corso: First cycle degree programme (L) in Industrial Chemistry (cod. 8513)

Learning outcomes

The aim of this Course is to acquaint the Student with enzymology. In particular, the Student will acquire knowledge about the structural properties of proteins and enzymes, and he will get familiar with enzyme kinetics and mechanisms. In addition, the use of enzymes in different industrial fields will also be discussed.

Course contents

Amino acids and proteins. Primary structure of proteins. Elements of secondary structure (alfa helix, beta strand, left-handed beta helix) and their interactions. Tertiary Structure. Structural motifs. General and enzyme kinetics. Enzyme catalysis and mechanisms of enzyme-catalyzed reactions. Enzymes in non-conventional media. Biosensors. Protein and enzyme engineering. Industrial enzymology.

Readings/Bibliography

1) Brandon, Tooze: Introduction to Protein Structure, Garland Publishing, New York. 2) Fersht: Enzyme Structure and Mechanism, Freeman, San Francisco.

Teaching methods

PowerPoint presentations.

Assessment methods

Written Test.

Office hours

See the website of Alejandro Hochkoeppler