Abstract
The development of age-appropriate and personalized medicines is still a necessity. For pediatric use, formulations must be tailored to accommodate child-specific characteristics such as age, weight, and swallowing ability. Moreover, specifically to antibiotic therapy, relevant limitations can be mentioned such as drug inappropriate biopharmaceutical properties, low stability in the gastrointestinal tract and bitter taste. The project p3Diatrics explored and combined innovative strategies with the final aim of obtaining suitable oral antibiotic formulations, specifically designed for various pediatric age groups. Formulations were manufactured using different 3D printing methodologies and characterized as regard the physico-chemical, technological, and functional properties. By combining both materials science and formulation technology fields, p3diatrics could impact current clinical scenarios, providing personalized dosage forms able to improve patient adherence to the therapy.
Project details
Unibo Team Leader: Angela Abruzzo
Unibo involved Department/s:
Dipartimento di Farmacia e Biotecnologie
Coordinator:
Università degli Studi di URBINO "Carlo Bo"(Italy)
Total Unibo Contribution: Euro (EUR) 57.786,00
Project Duration in months: 24
Start Date:
16/10/2023
End Date:
15/10/2025
