BISNES

Bio-Inspired Self-assembled Nano-Enabled Surfaces

Advanced nanofabrication can produce now nano-structures similar in size with single biomolecules or their self-assembled architectures. Capitalising on this strategic opportunity, BISNES focuses on the design, fabrication and implementation of biomimetic nanostructures which complement biomolecular surfaces and modulate the biomolecular activity.
The BISNES project will

  1. develop software products for the representation and quantification of bimolecular surfaces, especially those that self-assemble in long-range nano-aggregates, interacting with artificial nanostructures;
  2. design and fabricate nanostructured surfaces and objects that complementary replicate biomolecular surfaces; and design, fabricate and implement novel hybrid bio-devices which exhibit quantum-leap increase in capabilities (e.g., sensitivity, response time, cost) or entirely new ones.

 

The project will deliver demonstrated technical solutions with impact on a wide range of applications and products: ultra-sensitive bio-diagnostics and drug discovery devices; inherently bactericidal surfaces, medical devices for the in vitro study of amyloid and cytoskeleton proteins central to critical disease (e.g., neurodegenerative diseases, cancer); and hybrid nanodevices that exhibit new electromagnetic properties useful for future IT devices.

Coordinator
THE UNIVERSITY OF LIVERPOOL (UK)


Other participants
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA

  • Dip. di Scienze Farmaceutiche
  • Resp. scientifico: Prof.ssa Vincenza Andrisano

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (France)
NIL TECHNOLOGY APS - NILT NANOMASK APS (Dominica)
IMS NANOFABRICATION AG (Austria)
MONASH UNIVERSITY (Australia)
STICHTING BIOMADE TECHNOLOGY (The Netherlands)
PHILIPS ELECTRONICS NEDERLAND B.V. (The Netherlands)
UNIVERSITATEA POLITEHNICA DIN BUCURESTI (Romania)

 

Start date 01/09/2008

End date 31/08/2011

Duration 36 months

Project cost 4590000 Euro

Project Funding 2876280 Euro

Subprogramme Areas Self-assembling and self-organisation;
Nano-scale mechanisms of bio/non-bio interactions

Contract type Small or medium-scale focused research project