- Docente: Marcella Martinelli
- Credits: 5
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: Single cycle degree programme (LMCU) in Medicine and Surgery (cod. 8415)
Course contents
General characteristics of the cell
Prokaryotes and eukaryotes General organization of the cell. Syncytia and plasmodia.
Cell membrane
Membrane structure and functions Fluid mosaic. Transport across cell membranes. Glycocalyx. Non-junctional adhesiveness. Permeability. Specializations.
Cytoskeleton
Microfilaments. Intermediate filaments. Microtubules. Composition and function of microfilaments. Amoeboid movement. Actin and ancillary proteins. Contractility of the cell. - Composition and function of the intermediate filaments. - Microtubules: tubulin, ancillary proteins and microtubule-organizing centers. Cilia and flagella
Intercellular junctions.
Cytoplasm
Cytosol and inclusions Chemical composition, physical properties, and functions of the cytosol.
Cytoplasmic organelles
Endoplasmic reticulum Structure and functions of rough and smooth reticulum.
Apparatus of Golgi Structure and functions. Vesicular transport. Exocytosis.
Lysosomes Structure and functions. Endocytosis. Clathrin-mediated endocytosis. Phagocytosis. Autophagocytosis.
Peroxisomes structure and function.
Mitochondria Size, shape, and structural organization of mitochondria. Functions and origin of the mitochondria. Mitochondrial DNA.
Nucleus Number, size and localization of the interkinetic nucleus. The nucleolus end the biogenesis of ribosomes.
Readings/Bibliography
Adamo et al. "Istologia di V. Monesi" editor Piccin VI edition+ Cooper e Hausman "Fondamenti di Citologia" editore Piccin
Ginelli E, Malcovati M et al. "Molecole, Cellule e Organismi" editorrEdiSES
Bacci et al. "BIOLOGIA: Cellula e Tessuti" editorr EdiErmes
Bani et al. "Istologia Umana" editorr Idelson-Gnocchi
Bani et al. "Il manuale di Istologia" editor Idelson-Gnocchi
Rosati "Citologia ed Istologia" editor EdiErmes
Zaccheo and Pestarino "Citologia, Istologia e Anatomia Microscopica" editor Pearson
Teaching methods
Frontal lessons
Assessment methods
The learning assessment will include the examination of slides at light microscopy that is introductory to the oral exam. The students who failed the slide test are not admitted to the oral exam. The oral exam is a conversation about Cytology, Histology and Embryology according to the contents published in Histology and Embryology 1 and Histology and Embryology 2 courses. A low mark in one of the three parts precludes the whole exam. The student can choose to keep the mark of examination of slides (valid until December 2018) or to repeat it. In the opinion of the examiners, the final assessment will be the weighted average of the three results.
The online registration to the examination is mandatory.
Teaching tools
PowerPoint presentations. The material used during the lessons is available since the first lesson by login at AMS Campus-AlmaDL-Università di Bologna, after enrolment in the teacher's distribution list.
Office hours
See the website of Marcella Martinelli