Perez-Areales F.J.; Turcu A.L.; Barniol-Xicota M.; Pont C.; Pivetta D.; Espargaro A.; Bartolini M.; De Simone A.; Andrisano V.; Perez B.; Sabate R.; Sureda F.X.; Vazquez S.; Munoz-Torrero D., A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 180, pp. 613 - 626 [Scientific article]
Oukoloff, K.; Coquelle, N.; Bartolini, M.; Naldi, M.; Le Guevel, R.; Bach, S.; Josselin, B.; Ruchaud, S.; Catto, M.; Pisani, L.; Denora, N.; Iacobazzi, R. M.; Silman, I.; Sussman, J. L.; Buron, F.; Colletier, J. -P.; Jean, L.; Routier, S.; Renard, P. -Y., Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 168, pp. 58 - 77 [Scientific article]
Montanari S.; Mahmoud A.M.; Pruccoli L.; Rabbito A.; Naldi M.; Petralla S.; Moraleda I.; Bartolini M.; Monti B.; Iriepa I.; Belluti F.; Gobbi S.; Di Marzo V.; Bisi A.; Tarozzi A.; Ligresti A.; Rampa A., Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 178, pp. 243 - 258 [Scientific article]Open Access
Scheiner M.; Dolles D.; Gunesch S.; Hoffmann M.; Nabissi M.; Marinelli O.; Naldi M.; Bartolini M.; Petralla S.; Poeta E.; Monti B.; Falkeis C.; Vieth M.; Hubner H.; Gmeiner P.; Maitra R.; Maurice T.; Decker M., Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo, «JOURNAL OF MEDICINAL CHEMISTRY», 2019, 62, pp. 9078 - 9102 [Scientific article]Open Access
De Simone, Angela*; Naldi, Marina; Bartolini, Manuela; Davani, Lara; Andrisano, Vincenza, Immobilized Enzyme Reactors: an Overview of Applications in Drug Discovery from 2008 to 2018, «CHROMATOGRAPHIA», 2019, 82, pp. 425 - 441 [Scientific article]
De Simone A.; Naldi M.; Tedesco D.; Milelli A.; Bartolini M.; Davani L.; Widera D.; Dallas M.L.; Andrisano V., Investigating in vitro amyloid peptide 1−42 aggregation: Impact of higher molecular weight stable adducts, «ACS OMEGA», 2019, 4, pp. 12308 - 12318 [Scientific article]Open Access
Tramarin, Anna; Tedesco, Daniele; Naldi, Marina; Baldassarre, Maurizio; Bertucci, Carlo; Bartolini, Manuela*, New insights into the altered binding capacity of pharmaceutical-grade human serum albumin: site-specific binding studies by induced circular dichroism spectroscopy, «JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS», 2019, 162, pp. 171 - 178 [Scientific article]
Chalupova, K.; Korabecny, J.; Bartolini, M.; Monti, B.; Lamba, D.; Caliandro, R.; Pesaresi, A.; Brazzolotto, X.; Gastellier, A. -J.; Nachon, F.; Pejchal, J.; Jarosova, M.; Hepnarova, V.; Jun, D.; Hrabinova, M.; Dolezal, R.; Zdarova Karasova, J.; Mzik, M.; Kristofikova, Z.; Misik, J.; Muckova, L.; Jost, P.; Soukup, O.; Benkova, M.; Setnicka, V.; Habartova, L.; Chvojkova, M.; Kleteckova, L.; Vales, K.; Mezeiova, E.; Uliassi, E.; Valis, M.; Nepovimova, E.; Bolognesi, M. L.; Kuca, K., Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 168, pp. 491 - 514 [Scientific article]Open Access
Ramos, E.; Palomino-Antolin, A.; Bartolini, M.; Iriepa, I.; Moraleda, I.; Diez-Iriepa, D.; Samadi, A.; Cortina, C. V.; Chioua, M.; Egea, J.; Romero, A.; Marco-Contelles, J., Quinoxalinetacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy, «MOLECULES», 2019, 24, pp. 1503 - 1514 [Scientific article]Open Access
Fabini E.; Manoni E.; Ferroni C.; Del Rio A.; Bartolini M., Small-molecule inhibitors of lysine methyltransferases SMYD2 and SMYD3: Current trends, «FUTURE MEDICINAL CHEMISTRY», 2019, 11, pp. 901 - 921 [Scientific article]
Bertoni S., Tedesco D., Bartolini M., Passerini N., Albertini B., Solid lipid microparticles for oral delivery of catalase: focus on the protein integrity and gastric protection, in: 3rd European Conference on Pharmaceutics, 2019, pp. 1 - 2 (atti di: 3rd European Conference on Pharmaceutics, Bologna, 25-26 March 2019) [Contribution to conference proceedings]
AlFadly E.D.; Elzahhar P.A.; Tramarin A.; Elkazaz S.; Shaltout H.; Abu-Serie M.M.; Janockova J.; Soukup O.; Ghareeb D.A.; El-Yazbi A.F.; Rafeh R.W.; Bakkar N.-M.Z.; Kobeissy F.; Iriepa I.; Moraleda I.; Saudi M.N.S.; Bartolini M.; Belal A.S.F., Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 167, pp. 161 - 186 [Scientific article]
Roldan-Pena J.M.; Romero-Real V.; Hicke J.; Maya I.; Franconetti A.; Lagunes I.; Padron J.M.; Petralla S.; Poeta E.; Naldi M.; Bartolini M.; Monti B.; Bolognesi M.; Lopez O.; Fernandez-Bolanos J.G., Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 181, Article number: 111550 , pp. 111550 - 111565 [Scientific article]
Bartolini, Manuela*; Marco-Contelles, José, Tacrines as Therapeutic Agents for Alzheimer's Disease. IV. The Tacripyrines and Related Annulated Tacrines, «THE CHEMICAL RECORD», 2019, 19, pp. 927 - 937 [Scientific article]
Fabini E.; Talibov V.O.; Mihalic F.; Naldi M.; Bartolini M.; Bertucci C.; Del Rio A.; Danielson U.H., Unveiling the Biochemistry of the Epigenetic Regulator SMYD3, «BIOCHEMISTRY», 2019, 58, pp. 3634 - 3645 [Scientific article]
