Naldi M.; Brusotti G.; Massolini G.; Andrisano V.; Temporini C.; Bartolini M., Bio-guided fractionation of stem bark extracts from phyllanthus muellarianus: Identification of phytocomponents with anti-cholinesterase activity, «MOLECULES», 2021, 26, Article number: 4376 , pp. 4376-1 - 4376-14 [Scientific article]Open Access
Baldassarre M.; Naldi M.; Zaccherini G.; Bartoletti M.; Antognoli A.; Laggetta M.; Gagliardi M.; Tufoni M.; Domenicali M.; Waterstradt K.; Paterini P.; Baldan A.; Leoni S.; Bartolini M.; Viale P.; Trevisani F.; Bernardi M.; Caraceni P., Determination of Effective Albumin in Patients With Decompensated Cirrhosis: Clinical and Prognostic Implications, «HEPATOLOGY», 2021, 74, pp. 2058 - 2073 [Scientific article]Open Access
Viayna, Elisabet; Coquelle, Nicolas; Cieslikiewicz-Bouet, Monika; Cisternas, Pedro; Oliva, Carolina A.; Sánchez-López, Elena; Ettcheto, Miren; Bartolini, Manuela; De Simone, Angela; Ricchini, Mattia; Rendina, Marisa; Pons, Mégane; Firuzi, Omidreza; Pérez, Belén; Saso, Luciano; Andrisano, Vincenza; Nachon, Florian; Brazzolotto, Xavier; García, Maria Luisa; Camins, Antoni; Silman, Israel; Jean, Ludovic; Inestrosa, Nibaldo C.; Colletier, Jacques-Philippe; Renard, Pierre-Yves; Muñoz-Torrero, Diego, Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice, «JOURNAL OF MEDICINAL CHEMISTRY», 2021, 64, pp. 812 - 839 [Scientific article]
Talibov, Vladimir O; Fabini, Edoardo; FitzGerald, Edward A; Tedesco, Daniele; Cederfeldt, Daniela; Talu, Martin J; Rachman, Moira M; Mihalic, Filip; Manoni, Elisabetta; Naldi, Marina; Sanese, Paola; Forte, Giovanna; Lepore Signorile, Martina; Barril, Xavier; Simone, Cristiano; Bartolini, Manuela; Dobritzsch, Doreen; Del Rio, Alberto; Danielson, U Helena, Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase, «CHEMBIOCHEM», 2021, 22, pp. 1597 - 1608 [Scientific article]Open Access
Ramos, GD; de Oliveira, AS; Bartolini, M; Naldi, M; Liparulo, I; Bergamini, C; Uliassi, E; Wu, L; Fraser, PE; Abreu, M; Kiametis, AS; Gargano, R; Silveira, ER; Brand, GD; Prchal, L; Soukup, O; Korabecny, J; Bolognesi, ML; Romeiro, LAS, Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties, «RSC MEDICINAL CHEMISTRY», 2021, 12, pp. 1154 - 1163 [Scientific article]Open Access
Albertini C.; Naldi M.; Petralla S.; Strocchi S.; Grifoni D.; Monti B.; Bartolini M.; Bolognesi M.L., From combinations to single-molecule polypharmacology—cromolyn-ibuprofen conjugates for alzheimer’s disease, «MOLECULES», 2021, 26, Article number: 1112 , pp. 1 - 22 [Scientific article]Open Access
Pont C.; Ginex T.; Grinan-Ferre C.; Scheiner M.; Mattellone A.; Martinez N.; Arce E.M.; Soriano-Fernandez Y.; Naldi M.; De Simone A.; Barenys M.; Gomez-Catalan J.; Perez B.; Sabate R.; Andrisano V.; Loza M.I.; Brea J.; Bartolini M.; Bolognesi M.L.; Decker M.; Pallas M.; Luque F.J.; Munoz-Torrero D., From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2021, 225, Article number: 113779 , pp. 1 - 25 [Scientific article]Open Access
Montanari S.; Allara M.; Scalvini L.; Kostrzewa M.; Belluti F.; Gobbi S.; Naldi M.; Rivara S.; Bartolini M.; Ligresti A.; Bisi A.; Rampa A., New Coumarin derivatives as cholinergic and cannabinoid system modulators, «MOLECULES», 2021, 26, Article number: 3254 , pp. 1 - 18 [Scientific article]Open Access
Gorecki L.; Uliassi E.; Bartolini M.; Janockova J.; Hrabinova M.; Hepnarova V.; Prchal L.; Muckova L.; Pejchal J.; Karasova J.Z.; Mezeiova E.; Benkova M.; Kobrlova T.; Soukup O.; Petralla S.; Monti B.; Korabecny J.; Bolognesi M.L., Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease, «ACS CHEMICAL NEUROSCIENCE», 2021, 12, pp. 1698 - 1715 [Scientific article]
Rossi M, Freschi M, de Camargo Nascente L, Salerno A, de Melo Viana Teixeira S, Nachon F, Chantegreil F, Soukup O, Prchal L, Malaguti M, Bergamini C, Bartolini M, Angeloni C, Hrelia S, Soares Romeiro LA, Bolognesi ML., Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease, «JOURNAL OF MEDICINAL CHEMISTRY», 2021, 64, pp. 4972 - 4990 [Scientific article]Open Access
Perone R.; Albertini C.; Uliassi E.; Di Pietri F.; de Sena Murteira Pinheiro P.; Petralla S.; Rizzardi N.; Fato R.; Pulkrabkova L.; Soukup O.; Tramarin A.; Bartolini M.; Bolognesi M.L., Turning Donepezil into a Multi-Target-Directed Ligand through a Merging Strategy, «CHEMMEDCHEM», 2021, 16, pp. 187 - 198 [Scientific article]Open Access
De Simone A.; Naldi M.; Tedesco D.; Bartolini M.; Davani L.; Andrisano V., Advanced analytical methodologies in Alzheimer's disease drug discovery, «JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS», 2020, 178, Article number: 112899 , pp. 1 - 25 [Scientific article]
Pérez-Areales, F Javier; Garrido, María; Aso, Ester; Bartolini, Manuela; De Simone, Angela; Espargaró, Alba; Ginex, Tiziana; Sabate, Raimon; Pérez, Belén; Andrisano, Vincenza; Puigoriol-Illamola, Dolors; Pallàs, Mercè; Luque, F Javier; Loza, María Isabel; Brea, José; Ferrer, Isidro; Ciruela, Francisco; Messeguer, Angel; Muñoz-Torrero, Diego, Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6, «JOURNAL OF MEDICINAL CHEMISTRY», 2020, 63, pp. 9360 - 9390 [Scientific article]
Guzman, Laura; Besa, Gisela; Linares, Daniela; González, Lara; Pont, Caterina; Bartolini, Manuela; Haigis, Ann-Cathrin; Legradi, Jessica; Muñoz-Torrero, Diego; Gómez-Catalán, Jesús; Barenys, Marta, Evaluation of the effects of acetylcholinesterase inhibitors in the zebrafish touch-evoked response: quantitative vs. qualitative assessment, «ENVIRONMENTAL SCIENCES EUROPE», 2020, 32, Article number: 145 , pp. 1 - 12 [Scientific article]Open Access
Cieslikiewicz-Bouet, Monika; Naldi, Marina; Bartolini, Manuela; Pérez, Belén; Servent, Denis; Jean, Ludovic; Aráoz, Rómulo; Renard, Pierre-Yves, Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor, «BIOCHEMICAL PHARMACOLOGY», 2020, 177, Article number: 114010 , pp. 1 - 11 [Scientific article]
