Foto del docente

Manuela Bartolini

Full Professor

Department of Pharmacy and Biotechnology

Academic discipline: CHEM-07/A Pharmaceutical Chemistry

Publications

Ruolo editoriale nella rivista «Chromatographia»

Mensah, W. A.; Nabergoj, M.; Peljhan, S.; Naldi, M.; Bartolini, M., Immobilized enzyme reactors as enabling technologies for automated multidimensional analytical workflows in the era of complex therapeutics, «TALANTA», 2027, 312, Article number: 130429 , pp. 1 - 24 [Scientific article]

Nugnes, M.; Baldassarre, M.; Caraceni, P.; Naldi, M.; Bartolini, M., Albumin-on-a-chip: binding profiling of circulating human albumin via selective immunocapture and real-time SPR analysis, «SCIENTIFIC REPORTS», 2026, 16, Article number: 10920 , pp. 1 - 12 [Scientific article]Open Access

Hassan, N. W.; Afifi, O. S.; El-Attar, M. A. Z.; Kamel, Y. N.; Yassin, H. A.; Nomeir, H. M.; Angeli, A.; Labib, H. F.; Elsheikh, M. A.; Zewail, M.; Gerges, E. M.; El-Yazbi, A. F.; Spagnuolo, R.; Naldi, M.; Ashmawy, M. I.; Zahra, W. K.; Hammad, S. F.; Supuran, C. T.; Bartolini, M.; Elzahhar, P. A.; Belal, A. S. F.; Abd El Wahab, S. M., One destination, three routes: Tacrine-Celecoxib hybrids targeting cholinesterases, COX-2, and carbonic anhydrases in cognitive impairment linked to metabolic dysfunction, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2026, 315, Article number: 118984 , pp. 1 - 22 [Scientific article]

Osman, Shams T.; Elzahhar, Perihan A.; Hakim, Md Abdul; Sanni, Akeem; Hamdy, Noha A.; Purba, Waziha Tasnim; Bhuiyan, Md Mostofa Al Amin; Onigbinde, Sherifdeen; Sandilya, Vishal; Hassan, Nayera W.; Agami, Mahmoud; El‐khordagui, Labiba K.; Spagnuolo, Rosaria; Naldi, Marina; Bartolini, Manuela; Belal, Ahmed S. F.; Mechref, Yehia S.; El‐yazbi, Ahmed F., Repurposing SGLT2 and DPP‐4 inhibitors for mild cognitive impairment in type 2 diabetes mellitus: Insights from proteomics, target prediction and molecular docking, «BRITISH JOURNAL OF PHARMACOLOGY», 2026, 183, pp. 2533 - 2555 [Scientific article]

Castellino, I.; Bartolini, M.; Andrys, R.; Musilek, K., Small-Molecule Kinase Inhibitors Modulating Circadian Rhythms, «MEDICINAL RESEARCH REVIEWS», 2026, 46, pp. 1 - 18 [Scientific article]Open Access

Verano, Aldrick B.; Sampietro, Anna; Mallo-Abreu, Ana; Spagnuolo, Rosaria; Pérez, Belén; Bartolini, Manuela; Loza, María Isabel; Brea, José; Juárez-Jiménez, Jordi; Sabate, Raimon; Galdeano, Carles; Muñoz-Torrero, Diego, Synthesis and Biological Profiling of New 1,2,3,4-Tetrahydrobenzo[h]naphthyridine-Based Hybrids as Dual Inhibitors of β-Amyloid and Tau Aggregation with Anticholinesterase Activity, «BIOMOLECULES», 2026, 16, Article number: 593 , pp. 1 - 32 [Scientific article]Open Access

Bartolini, M., Cholinesterase Inhibition for the Treatment of Neurodegenerative Diseases: Assay Methodologies and Reference Compounds, in: Methods in Neurodegenerative Disease Drug Discovery, New York, Springer Nature, 2025, pp. 167 - 189 (NEUROMETHODS) [Chapter or essay]

Orioli, R.; Sarno, G.; Seghetti, F.; Gobbi, S.; Belluti, F.; Feoli, A.; Massenzio, F.; Monti, B.; Spagnuolo, R.; Bartolini, M.; Castellano, S.; Bisi, A., Exploiting acylaminopyrazole scaffold for polypharmacology approach in Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2025, 295, pp. 117799 - 117816 [Scientific article]Open Access

Santos Evangelista, T. C.; González-Bakker, A.; Puerta, A.; Poeta, E.; Monti, B.; Naldi, M.; Bolognesi, M. L.; Bartolini, M.; Vaaland Holmgard, I. C.; Butt, A.; Padrón, J. M.; Fernández-Bolaños, J. G.; Sydnes, M. O.; Lindbäck, E.; López, Ó., Isofagomine-coumarin hybrids: bridging cancer and Alzheimer's disease, «CHEMICO-BIOLOGICAL INTERACTIONS», 2025, 420, pp. 1 - 14 [Scientific article]Open Access

Elzahhar, Perihan A.; Nematalla, Hisham A.; Abouayana, Malak A.; El Ashry, El Sayed H.; Balbaa, Mahmoud; Petreni, Andrea; Nassra, Rasha; Yassin, Hend A.; Kamel, Yasmine N.; Elrewiny, Mohamed A.; Agami, Mahmoud A.; Makkar, Monica; Sai, Minh; Merk, Daniel; Labib, Hala F.; Spagnuolo, Rosaria; Naldi, Marina; Bartolini, Manuela; El-Hawash, Soad A.; Supuran, Claudiu T.; Belal, Ahmed S. F.; El-Yazbi, Ahmed F., Multi-Target Glitazones for Modulating Peroxisome Proliferator-Activated Receptor-γ, Cyclooxygenase-2, and Carbonic Anhydrases for the Management of Metabolic Dysfunction, «ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE», 2025, 8, pp. 1627 - 1658 [Scientific article]

Nugnes, M.; Baldassarre, M.; Ribichini, D.; Tedesco, D.; Capelli, I.; Vetrano, D.; Marchignoli, F.; Brodosi, L.; Pompili, E.; Petroni, M. L.; La Manna, G.; Marchesini, G.; Naldi, M.; Bartolini, M., Association between Albumin Alterations and Renal Function in Patients with Type 2 Diabetes Mellitus, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2024, 25, Article number: 3168 , pp. 1 - 15 [Scientific article]Open Access

Orioli, Rebecca; Feoli, Alessandra; Gobbi, Silvia; Belluti, Federica; Bartolini, Manuela; Castellano, Sabrina; Bisi, Alessandra, Exploiting the pyrazole scaffold for multipotent agents in Alzheimer’s disease, in: Poster, 2024(atti di: XXVIII CONGRESSO NAZIONALE SCI, Milano, 26-30 agosto 2024) [Poster]

Tubertini M.; Menilli L.; Milani C.; Martini C.; Navacchia M.L.; Nugnes M.; Bartolini M.; Naldi M.; Tedesco D.; Martella E.; Guerrini A.; Ferroni C.; Moret F.; Varchi G., HSA-nanobinders crafted from bioresponsive prodrugs for combined cancer chemoimmunotherapy–an in vitro exploration, «FRONTIERS IN CHEMISTRY», 2024, 12, Article number: 1378233 , pp. 01 - 18 [Scientific article]Open Access

Bayraktar, Gülşah; Bartolini, Manuela; Bolognesi, Maria Laura; Erdoğan, Mumin Alper; Armağan, Güliz; Bayır, Ece; Şendemir, Aylin; Bagetta, Donatella; Alcaro, Stefano; Alptüzün, Vildan, Novel multifunctional tacrine–donepezil hybrids against Alzheimer's disease: Design synthesis and bioactivity studies, «ARCHIV DER PHARMAZIE», 2024, 357, Article number: 2300575 , pp. 1 - 19 [Scientific article]Open Access