Foto del docente

Manuela Bartolini

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: CHIM/08 Pharmaceutical Chemistry

Publications

Ruolo editoriale nella rivista «Chromatographia»

De Simone A.; Naldi M.; Tedesco D.; Bartolini M.; Davani L.; Andrisano V., Advanced analytical methodologies in Alzheimer's disease drug discovery, «JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS», 2020, 178, pp. 1 - 25 [Scientific article]

Perez-Areales F.J.; Turcu A.L.; Barniol-Xicota M.; Pont C.; Pivetta D.; Espargaro A.; Bartolini M.; De Simone A.; Andrisano V.; Perez B.; Sabate R.; Sureda F.X.; Vazquez S.; Munoz-Torrero D., A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 180, pp. 613 - 626 [Scientific article]

Oukoloff K.; Coquelle N.; Bartolini M.; Naldi M.; Le Guevel R.; Bach S.; Josselin B.; Ruchaud S.; Catto M.; Pisani L.; Denora N.; Iacobazzi R.M.; Silman I.; Sussman J.L.; Buron F.; Colletier J.-P.; Jean L.; Routier S.; Renard P.-Y., Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 168, pp. 58 - 77 [Scientific article]

Montanari S.; Mahmoud A.M.; Pruccoli L.; Rabbito A.; Naldi M.; Petralla S.; Moraleda I.; Bartolini M.; Monti B.; Iriepa I.; Belluti F.; Gobbi S.; Di Marzo V.; Bisi A.; Tarozzi A.; Ligresti A.; Rampa A., Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 178, pp. 243 - 258 [Scientific article]

De Simone, Angela*; Naldi, Marina; Bartolini, Manuela; Davani, Lara; Andrisano, Vincenza, Immobilized Enzyme Reactors: an Overview of Applications in Drug Discovery from 2008 to 2018, «CHROMATOGRAPHIA», 2019, 82, pp. 425 - 441 [Scientific article]

De Simone A.; Naldi M.; Tedesco D.; Milelli A.; Bartolini M.; Davani L.; Widera D.; Dallas M.L.; Andrisano V., Investigating in vitro amyloid peptide 1−42 aggregation: Impact of higher molecular weight stable adducts, «ACS OMEGA», 2019, 4, pp. 12308 - 12318 [Scientific article]

Tramarin, Anna; Tedesco, Daniele; Naldi, Marina; Baldassarre, Maurizio; Bertucci, Carlo; Bartolini, Manuela*, New insights into the altered binding capacity of pharmaceutical-grade human serum albumin: site-specific binding studies by induced circular dichroism spectroscopy, «JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS», 2019, 162, pp. 171 - 178 [Scientific article]

Chalupova K.; Korabecny J.; Bartolini M.; Monti B.; Lamba D.; Caliandro R.; Pesaresi A.; Brazzolotto X.; Gastellier A.-J.; Nachon F.; Pejchal J.; Jarosova M.; Hepnarova V.; Jun D.; Hrabinova M.; Dolezal R.; Zdarova Karasova J.; Mzik M.; Kristofikova Z.; Misik J.; Muckova L.; Jost P.; Soukup O.; Benkova M.; Setnicka V.; Habartova L.; Chvojkova M.; Kleteckova L.; Vales K.; Mezeiova E.; Uliassi E.; Valis M.; Nepovimova E.; Bolognesi M.L.; Kuca K., Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 168, pp. 491 - 514 [Scientific article]

Ramos E.; Palomino-Antolin A.; Bartolini M.; Iriepa I.; Moraleda I.; Diez-Iriepa D.; Samadi A.; Cortina C.V.; Chioua M.; Egea J.; Romero A.; Marco-Contelles J., Quinoxalinetacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy, «MOLECULES», 2019, 24, pp. 1503 - 1514 [Scientific article]

Fabini E.; Manoni E.; Ferroni C.; Del Rio A.; Bartolini M., Small-molecule inhibitors of lysine methyltransferases SMYD2 and SMYD3: Current trends, «FUTURE MEDICINAL CHEMISTRY», 2019, 11, pp. 901 - 921 [Scientific article]

AlFadly E.D.; Elzahhar P.A.; Tramarin A.; Elkazaz S.; Shaltout H.; Abu-Serie M.M.; Janockova J.; Soukup O.; Ghareeb D.A.; El-Yazbi A.F.; Rafeh R.W.; Bakkar N.-M.Z.; Kobeissy F.; Iriepa I.; Moraleda I.; Saudi M.N.S.; Bartolini M.; Belal A.S.F., Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 167, pp. 161 - 186 [Scientific article]

Bartolini, Manuela*; Marco-Contelles, José, Tacrines as Therapeutic Agents for Alzheimer's Disease. IV. The Tacripyrines and Related Annulated Tacrines, «THE CHEMICAL RECORD», 2019, 19, pp. 927 - 937 [Scientific article]

Fabini E.; Talibov V.O.; Mihalic F.; Naldi M.; Bartolini M.; Bertucci C.; Del Rio A.; Danielson U.H., Unveiling the Biochemistry of the Epigenetic Regulator SMYD3, «BIOCHEMISTRY», 2019, 58, pp. 3634 - 3645 [Scientific article]

de simone a, naldi m, tedesco d, bartolini m, andrisano v, A multi-methodological approach for the investigation of β-Amyloid-CORMs interaction: an LC-ESI/MS and Circular Dichroism study., in: 10° MS pharma day book of abstracts, 2018, pp. 15 - 16 (atti di: 10° MS pharma day, Colleretto Giacosa (TO), 24-26 Ottobre) [Contribution to conference proceedings]