- Alzheimer's disease. Studies of structure-activity relationships and mechanism of action of new synthetic and natural compounds on target enzymes (acetylcholinesterase and butyrylcolinesterase) and aggregation of beta amyloid peptide.
- Advanced analytical methods in drug discovery, glycomics and proteomics. Development of bioreactors containing immobilized enzymes for the on-line evaluation of biologically active compounds, for protein digestion in proteomic approaches and for protein deglycosylation in glycomic approaches.
- Diabetes mellitus. Investigation of the role of advanced glycation end-products in the onset of chronic complications of diabetes associated with RAGE activation.
- Investigation of biorecognition phenomena by optical biosensor.
