Foto del docente

Manuela Bartolini

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: CHIM/08 Pharmaceutical Chemistry

Curriculum vitae

Prof Bartolini got her master degree in Chemistry and Pharmaceutical Technology in 1998 at the University of Bologna and in 2003 she defended her PhD thesis titled “development of analytical methods for acetylcholinesterase (AChE) inhibitors characterization”. Since September 2015 she works as associate professor at the Department of Pharmacy and Biotechnology, University of Bologna. In 2001 she spent 8 months at the Gerontology Research Centre NIA/NIH, Baltimore, carrying out a research project aimed at the development and characterization of an immobilized enzyme reactor based on glyceraldehyde-3-phosphate dehydrogenase for on line enzymatic studies; in 2006 she worked as Maître Assistante at the Laboratory of Analytical Chemistry, University of Geneva (Switzerland) on the development of a cytochrome P450-based bioreactor for drug metabolism studies. Her work is mainly focused on: (1) development of fast automated analytical techniques based on immobilized enzymes reactors to screen and characterize new ligands for key target enzymes of pharmaceutical interest or with applications in proteomics and glycomics, (2) application of analytical techniques to monitor beta-amyloid aggregation both spontaneous and induced by human AChE, (3) investigation of albumin glycation and its role in the onset of chronic complications of diabetes mellitus.

During her carrer, international scientific collaborations have been established with the pharmaceutical Spanish company Neuropharma S.A., the University of Barcelona (Spain), the Institute of General Organic Chemistry (Madrid, Spain) and with Dr N.H. Greig at the Drug Design and Development Section (GRC/NIA/NIH, Baltimore, USA).

Since 2008 she is member of the organizing and scientific committees of the Summer school on Pharmaceutical Analysis and, since 2012, she is member of the editorial board of the journal "Chromatographia". In 2013 she acted as scientific secretary of the International Symposium on Pharmaceutical and Biomedical Analysis (PBA2017) and in 2017 she was member of the scientific committee and acted as scientific secretary of the international congress on the Recent Developments on Pharmaceutical Analysis ed. 2017 (RDPA2017). Since 2018 she is also member of the scientific commette of the congress MS Pharmaday.

Prof Bartolini is the author of 106 papers on international journals, 2 chapters in books (ILM publications and Società Editrice Esclulapio), 2 international patents and several oral communications at international congresses.