Foto del docente

Manuela Bartolini

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: CHIM/08 Pharmaceutical Chemistry

Publications

Palmerini, Tullio; Barozzi, Chiara; Tomasi, Luciana; Riva, Diego Della; Marengo, Mario; Cicoria, Gianfranco; Bruno, Antonio G.; Bacchi-Reggiani, Maria-Letizia; Naldi, Marina; Bartolini, Manuela; Fanti, Stefano; Galiè, Nazzareno; Stone, Gregg W., In vitro thrombogenicity of drug-eluting and bare metal stents, «THROMBOSIS RESEARCH», 2020, 185, pp. 43 - 48 [Scientific article]

Bua G.; Tedesco D.; Conti I.; Reggiani A.; Bartolini M.; Gallinella G., No G-Quadruplex Structures in the DNA of Parvovirus B19: Experimental Evidence versus Bioinformatic Predictions, «VIRUSES», 2020, 12, Article number: 935 , pp. 935 - 935 [Scientific article]Open Access

Marques C.S.; Lopez O.; Bagetta D.; Carreiro E.P.; Petralla S.; Bartolini M.; Hoffmann M.; Alcaro S.; Monti B.; Bolognesi M.L.; Decker M.; Fernandez-Bolanos J.G.; Burke A.J., N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study, «BIOORGANIC CHEMISTRY», 2020, 98, Article number: 103753 , pp. 103753 - 103765 [Scientific article]

Bertoni S.; Tedesco D.; Bartolini M.; Prata C.; Passerini N.; Albertini B., Solid Lipid Microparticles for Oral Delivery of Catalase: Focus on the Protein Structural Integrity and Gastric Protection, «MOLECULAR PHARMACEUTICS», 2020, 17, pp. 3609 - 3621 [Scientific article]Open Access

Sanese, Paola; Fasano, Candida; Buscemi, Giacomo; Bottino, Cinzia; Corbetta, Silvia; Fabini, Edoardo; Silvestri, Valentina; Valentini, Virginia; Disciglio, Vittoria; Forte, Giovanna; Lepore Signorile, Martina; De Marco, Katia; Bertora, Stefania; Grossi, Valentina; Guven, Ummu; Porta, Natale; Di Maio, Valeria; Manoni, Elisabetta; Giannelli, Gianluigi; Bartolini, Manuela; Del Rio, Alberto; Caretti, Giuseppina; Ottini, Laura; Simone, Cristiano, Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic Lethality, «ISCIENCE», 2020, 23, pp. 101604 - 101604 [Scientific article]Open Access

Tramarin, Anna; Naldi, Marina; Degani, Genny; Lupu, Loredana; Wiegand, Pascal; Mazzolari, Angelica; Altomare, Alessandra; Aldini, Giancarlo; Popolo, Laura; Vistoli, Giulio; Przybylski, Michael; Bartolini, Manuela, Unveiling the molecular mechanisms underpinning biorecognition of early-glycated human serum albumin and receptor for advanced glycation end products, «ANALYTICAL AND BIOANALYTICAL CHEMISTRY», 2020, 412, pp. 4245 - 4259 [Scientific article]

Perez-Areales F.J.; Turcu A.L.; Barniol-Xicota M.; Pont C.; Pivetta D.; Espargaro A.; Bartolini M.; De Simone A.; Andrisano V.; Perez B.; Sabate R.; Sureda F.X.; Vazquez S.; Munoz-Torrero D., A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 180, pp. 613 - 626 [Scientific article]

Oukoloff K.; Coquelle N.; Bartolini M.; Naldi M.; Le Guevel R.; Bach S.; Josselin B.; Ruchaud S.; Catto M.; Pisani L.; Denora N.; Iacobazzi R.M.; Silman I.; Sussman J.L.; Buron F.; Colletier J.-P.; Jean L.; Routier S.; Renard P.-Y., Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 168, pp. 58 - 77 [Scientific article]

Montanari S.; Mahmoud A.M.; Pruccoli L.; Rabbito A.; Naldi M.; Petralla S.; Moraleda I.; Bartolini M.; Monti B.; Iriepa I.; Belluti F.; Gobbi S.; Di Marzo V.; Bisi A.; Tarozzi A.; Ligresti A.; Rampa A., Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 178, pp. 243 - 258 [Scientific article]Open Access

Scheiner M.; Dolles D.; Gunesch S.; Hoffmann M.; Nabissi M.; Marinelli O.; Naldi M.; Bartolini M.; Petralla S.; Poeta E.; Monti B.; Falkeis C.; Vieth M.; Hubner H.; Gmeiner P.; Maitra R.; Maurice T.; Decker M., Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo, «JOURNAL OF MEDICINAL CHEMISTRY», 2019, 62, pp. 9078 - 9102 [Scientific article]Open Access

De Simone, Angela*; Naldi, Marina; Bartolini, Manuela; Davani, Lara; Andrisano, Vincenza, Immobilized Enzyme Reactors: an Overview of Applications in Drug Discovery from 2008 to 2018, «CHROMATOGRAPHIA», 2019, 82, pp. 425 - 441 [Scientific article]

De Simone A.; Naldi M.; Tedesco D.; Milelli A.; Bartolini M.; Davani L.; Widera D.; Dallas M.L.; Andrisano V., Investigating in vitro amyloid peptide 1−42 aggregation: Impact of higher molecular weight stable adducts, «ACS OMEGA», 2019, 4, pp. 12308 - 12318 [Scientific article]Open Access

Tramarin, Anna; Tedesco, Daniele; Naldi, Marina; Baldassarre, Maurizio; Bertucci, Carlo; Bartolini, Manuela*, New insights into the altered binding capacity of pharmaceutical-grade human serum albumin: site-specific binding studies by induced circular dichroism spectroscopy, «JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS», 2019, 162, pp. 171 - 178 [Scientific article]

Chalupova K.; Korabecny J.; Bartolini M.; Monti B.; Lamba D.; Caliandro R.; Pesaresi A.; Brazzolotto X.; Gastellier A.-J.; Nachon F.; Pejchal J.; Jarosova M.; Hepnarova V.; Jun D.; Hrabinova M.; Dolezal R.; Zdarova Karasova J.; Mzik M.; Kristofikova Z.; Misik J.; Muckova L.; Jost P.; Soukup O.; Benkova M.; Setnicka V.; Habartova L.; Chvojkova M.; Kleteckova L.; Vales K.; Mezeiova E.; Uliassi E.; Valis M.; Nepovimova E.; Bolognesi M.L.; Kuca K., Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 168, pp. 491 - 514 [Scientific article]Open Access

Ramos E.; Palomino-Antolin A.; Bartolini M.; Iriepa I.; Moraleda I.; Diez-Iriepa D.; Samadi A.; Cortina C.V.; Chioua M.; Egea J.; Romero A.; Marco-Contelles J., Quinoxalinetacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy, «MOLECULES», 2019, 24, pp. 1503 - 1514 [Scientific article]Open Access